Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review

Obesity–insulin resistance–β-cells apoptosis” is an important trilogy of the pathogenesis of type 2 diabetes. With the global pandemic of obesity and diabetes, continuous research and development of new drugs focuses on the prevention of the pathological progress of these diseases. According to a re...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Chen, Zhengtao, Zhao, Xiaoyan, Xie, Hongyan, Du, Lian, Gao, Hong, Xie, Chunguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490412/
https://www.ncbi.nlm.nih.gov/pubmed/36157449
http://dx.doi.org/10.3389/fendo.2022.990299
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author Yang, Yan
Chen, Zhengtao
Zhao, Xiaoyan
Xie, Hongyan
Du, Lian
Gao, Hong
Xie, Chunguang
author_facet Yang, Yan
Chen, Zhengtao
Zhao, Xiaoyan
Xie, Hongyan
Du, Lian
Gao, Hong
Xie, Chunguang
author_sort Yang, Yan
collection PubMed
description Obesity–insulin resistance–β-cells apoptosis” is an important trilogy of the pathogenesis of type 2 diabetes. With the global pandemic of obesity and diabetes, continuous research and development of new drugs focuses on the prevention of the pathological progress of these diseases. According to a recent study, the natural product kaempferol has excellent antidiabetic effects. Therefore, this review comprehensively summarized the frontier studies and pharmacological mechanisms of kaempferol in the treatment of diabetes. The successful research and development of kaempferol may yield a significant leap in the treatment of diabetes and its complications.
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spelling pubmed-94904122022-09-22 Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review Yang, Yan Chen, Zhengtao Zhao, Xiaoyan Xie, Hongyan Du, Lian Gao, Hong Xie, Chunguang Front Endocrinol (Lausanne) Endocrinology Obesity–insulin resistance–β-cells apoptosis” is an important trilogy of the pathogenesis of type 2 diabetes. With the global pandemic of obesity and diabetes, continuous research and development of new drugs focuses on the prevention of the pathological progress of these diseases. According to a recent study, the natural product kaempferol has excellent antidiabetic effects. Therefore, this review comprehensively summarized the frontier studies and pharmacological mechanisms of kaempferol in the treatment of diabetes. The successful research and development of kaempferol may yield a significant leap in the treatment of diabetes and its complications. Frontiers Media S.A. 2022-09-07 /pmc/articles/PMC9490412/ /pubmed/36157449 http://dx.doi.org/10.3389/fendo.2022.990299 Text en Copyright © 2022 Yang, Chen, Zhao, Xie, Du, Gao and Xie https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Yang, Yan
Chen, Zhengtao
Zhao, Xiaoyan
Xie, Hongyan
Du, Lian
Gao, Hong
Xie, Chunguang
Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review
title Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review
title_full Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review
title_fullStr Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review
title_full_unstemmed Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review
title_short Mechanisms of Kaempferol in the treatment of diabetes: A comprehensive and latest review
title_sort mechanisms of kaempferol in the treatment of diabetes: a comprehensive and latest review
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490412/
https://www.ncbi.nlm.nih.gov/pubmed/36157449
http://dx.doi.org/10.3389/fendo.2022.990299
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