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Integrating experimental model, LC-MS/MS chemical analysis, and systems biology approach to investigate the possible antidiabetic effect and mechanisms of Matricaria aurea (Golden Chamomile) in type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) is a heterogeneous disease with numerous abnormal targets and pathways involved in insulin resistance, low-grade inflammation, oxidative stress, beta cell dysfunction, and epigenetic factors. Botanical drugs provide a large chemical space that can modify various targe...
Autores principales: | Ismail, Yassin, Fahmy, Dina M., Ghattas, Maivel H., Ahmed, Mai M., Zehry, Walaa, Saleh, Samy M., Abo-elmatty, Dina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490514/ https://www.ncbi.nlm.nih.gov/pubmed/36160451 http://dx.doi.org/10.3389/fphar.2022.924478 |
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