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Divergent copper-catalyzed syntheses of 3-carboxylpyrroles and 3-cyanofurans from O-acetyl oximes and β-ketoesters/nitriles
The reaction between O-acetyl oximes and β-ketoesters/nitriles catalyzed by copper generated polysubstituted pyrroles and furans, respectively, under redox–neutral reaction conditions. Using this protocol, pyrroles or furans could be obtained simply by choosing an appropriate active methylene compou...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490516/ https://www.ncbi.nlm.nih.gov/pubmed/36275146 http://dx.doi.org/10.1039/d2ra04938d |
| Sumario: | The reaction between O-acetyl oximes and β-ketoesters/nitriles catalyzed by copper generated polysubstituted pyrroles and furans, respectively, under redox–neutral reaction conditions. Using this protocol, pyrroles or furans could be obtained simply by choosing an appropriate active methylene compound. Although both transformations occur essentially under the same reaction conditions, control experiments indicated that they follow different mechanistic pathways. |
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