Sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study

Babies in intensive care are at higher risk for meningitis and sensorineural hearing loss (SNHL). We reviewed the rate of SNHL among definite cases of bacterial/fungal meningitis in our neonatal intensive care unit over a 16-year period (2006–2021). We identified 16 confirmed meningitis cases among...

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Autores principales: Sharma, Ankur, Leaf, James M, Thomas, Saumya, Cane, Christine, Stuart, Claire, Tremlett, Catherine, Fitzgerald, John, Clarke, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Original Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490614/
https://www.ncbi.nlm.nih.gov/pubmed/36645772
http://dx.doi.org/10.1136/bmjpo-2022-001601
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author Sharma, Ankur
Leaf, James M
Thomas, Saumya
Cane, Christine
Stuart, Claire
Tremlett, Catherine
Fitzgerald, John
Clarke, Paul
author_facet Sharma, Ankur
Leaf, James M
Thomas, Saumya
Cane, Christine
Stuart, Claire
Tremlett, Catherine
Fitzgerald, John
Clarke, Paul
author_sort Sharma, Ankur
collection PubMed
description Babies in intensive care are at higher risk for meningitis and sensorineural hearing loss (SNHL). We reviewed the rate of SNHL among definite cases of bacterial/fungal meningitis in our neonatal intensive care unit over a 16-year period (2006–2021). We identified 16 confirmed meningitis cases among 16 070 admissions: 8 of 10 surviving infants with available diagnostic audiology had normal/satisfactory hearing while 2 of 10 had SNHL. Both infants with permanent hearing loss had been born extremely preterm and received potentially ototoxic antimicrobials. Larger studies are needed to clarify whether SNHL occurs mainly due to meningitis itself or to its antimicrobial drug treatment.
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spelling pubmed-94906142022-09-22 Sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study Sharma, Ankur Leaf, James M Thomas, Saumya Cane, Christine Stuart, Claire Tremlett, Catherine Fitzgerald, John Clarke, Paul BMJ Paediatr Open Original Research Letter Babies in intensive care are at higher risk for meningitis and sensorineural hearing loss (SNHL). We reviewed the rate of SNHL among definite cases of bacterial/fungal meningitis in our neonatal intensive care unit over a 16-year period (2006–2021). We identified 16 confirmed meningitis cases among 16 070 admissions: 8 of 10 surviving infants with available diagnostic audiology had normal/satisfactory hearing while 2 of 10 had SNHL. Both infants with permanent hearing loss had been born extremely preterm and received potentially ototoxic antimicrobials. Larger studies are needed to clarify whether SNHL occurs mainly due to meningitis itself or to its antimicrobial drug treatment. BMJ Publishing Group 2022-09-20 /pmc/articles/PMC9490614/ /pubmed/36645772 http://dx.doi.org/10.1136/bmjpo-2022-001601 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research Letter
Sharma, Ankur
Leaf, James M
Thomas, Saumya
Cane, Christine
Stuart, Claire
Tremlett, Catherine
Fitzgerald, John
Clarke, Paul
Sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study
title Sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study
title_full Sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study
title_fullStr Sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study
title_full_unstemmed Sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study
title_short Sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study
title_sort sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study
topic Original Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490614/
https://www.ncbi.nlm.nih.gov/pubmed/36645772
http://dx.doi.org/10.1136/bmjpo-2022-001601
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