Stereoselective synthesis of C3-tetrasubstituted oxindoles via copper catalyzed asymmetric propargylation

Herein, a copper catalyzed asymmetric propargylation of 2-oxindole-3-carboxylate esters with terminal propargylic esters is described. This strategy successfully provides a direct approach to constructing a broad range of chiral C3-tetrasubstituted oxindoles with contiguous tertiary and quaternary c...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jiao-Mei, Zhao, Yu, Yao, Chang-Sheng, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490778/
https://www.ncbi.nlm.nih.gov/pubmed/36320842
http://dx.doi.org/10.1039/d2ra04603b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490778/
https://www.ncbi.nlm.nih.gov/pubmed/36320842
http://dx.doi.org/10.1039/d2ra04603b

Ejemplares similares