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Stereoselective synthesis of C3-tetrasubstituted oxindoles via copper catalyzed asymmetric propargylation

Herein, a copper catalyzed asymmetric propargylation of 2-oxindole-3-carboxylate esters with terminal propargylic esters is described. This strategy successfully provides a direct approach to constructing a broad range of chiral C3-tetrasubstituted oxindoles with contiguous tertiary and quaternary c...

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Detalles Bibliográficos
Autores principales:	Wang, Jiao-Mei, Zhao, Yu, Yao, Chang-Sheng, Zhang, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490778/ https://www.ncbi.nlm.nih.gov/pubmed/36320842 http://dx.doi.org/10.1039/d2ra04603b

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