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Characterization of ancestral Fe/Mn superoxide dismutases indicates their cambialistic origin

Superoxide dismutases (SODs) are critical metalloenzymes mitigating the damages of the modern oxygenated world. However, the emergence of one family of SODs, the Fe/Mn SOD, has been recurrently proposed to predate the great oxygenation event (GOE). This ancient family lacks metal binding selectivity...

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Detalles Bibliográficos
Autores principales: Valenti, Rosario, Jabłońska, Jagoda, Tawfik, Dan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490801/
https://www.ncbi.nlm.nih.gov/pubmed/36173172
http://dx.doi.org/10.1002/pro.4423

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