Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers

[Image: see text] A short, concise, and one-pot synthesis of imidazo-fused heterocycle dimers with tunable fluorescent properties has been developed. By the first time use of glyoxal dimethyl acetal in the Groebke–Blackburn–Bienaymé (GBB) three-component reaction (3CR), the innovation features a new...

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Autores principales: Zheng, Qiang, Li, Xin, Kurpiewska, Katarzyna, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490819/
https://www.ncbi.nlm.nih.gov/pubmed/35830622
http://dx.doi.org/10.1021/acs.orglett.2c01642
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author Zheng, Qiang
Li, Xin
Kurpiewska, Katarzyna
Dömling, Alexander
author_facet Zheng, Qiang
Li, Xin
Kurpiewska, Katarzyna
Dömling, Alexander
author_sort Zheng, Qiang
collection PubMed
description [Image: see text] A short, concise, and one-pot synthesis of imidazo-fused heterocycle dimers with tunable fluorescent properties has been developed. By the first time use of glyoxal dimethyl acetal in the Groebke–Blackburn–Bienaymé (GBB) three-component reaction (3CR), the innovation features a new series of fluorescence-tunable imidazo-fused heterocycle dimers exhibiting a broad substrate scope with good yields. Luminescence studies demonstrate that these GBB-dimers possess color-tunable properties, and their emission colors can be successively changed from blue to green and yellow by easy substituent control.
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spelling pubmed-94908192022-09-22 Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers Zheng, Qiang Li, Xin Kurpiewska, Katarzyna Dömling, Alexander Org Lett [Image: see text] A short, concise, and one-pot synthesis of imidazo-fused heterocycle dimers with tunable fluorescent properties has been developed. By the first time use of glyoxal dimethyl acetal in the Groebke–Blackburn–Bienaymé (GBB) three-component reaction (3CR), the innovation features a new series of fluorescence-tunable imidazo-fused heterocycle dimers exhibiting a broad substrate scope with good yields. Luminescence studies demonstrate that these GBB-dimers possess color-tunable properties, and their emission colors can be successively changed from blue to green and yellow by easy substituent control. American Chemical Society 2022-07-13 2022-07-22 /pmc/articles/PMC9490819/ /pubmed/35830622 http://dx.doi.org/10.1021/acs.orglett.2c01642 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Zheng, Qiang
Li, Xin
Kurpiewska, Katarzyna
Dömling, Alexander
Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers
title Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers
title_full Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers
title_fullStr Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers
title_full_unstemmed Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers
title_short Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers
title_sort synthesis of tunable fluorescent imidazole-fused heterocycle dimers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490819/
https://www.ncbi.nlm.nih.gov/pubmed/35830622
http://dx.doi.org/10.1021/acs.orglett.2c01642
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AT kurpiewskakatarzyna synthesisoftunablefluorescentimidazolefusedheterocycledimers
AT domlingalexander synthesisoftunablefluorescentimidazolefusedheterocycledimers

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