Elucidation of Structure–Activity Relationships in Indolobenzazepine-Derived Ligands and Their Copper(II) Complexes: the Role of Key Structural Components and Insight into the Mechanism of Action

[Image: see text] Indolo[3,2-d][1]benzazepines (paullones), indolo[3,2-d][2]benzazepines, and indolo[2,3-d][2]benzazepines (latonduines) are isomeric scaffolds of current medicinal interest. Herein, we prepared a small library of novel indolo[3,2-d][2]benzazepine-derived ligands HL(1)–HL(4) and copp...

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Autores principales: Kuznetcova, Irina, Bacher, Felix, Alfadul, Samah Mutasim, Tham, Max Jing Rui, Ang, Wee Han, Babak, Maria V., Rapta, Peter, Arion, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490829/
https://www.ncbi.nlm.nih.gov/pubmed/35713376
http://dx.doi.org/10.1021/acs.inorgchem.2c01375

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