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Catalytic Enantioselective Entry to Triflones Featuring a Quaternary Stereocenter

[Image: see text] A highly enantioselective one-pot synthesis of functionalized triflones, bearing a quaternary stereocenter, has been developed, exploiting the Michael reaction of α-(trifluoromethylsulfonyl) aryl acetic acid esters with N-acryloyl-1H-pyrazole catalyzed by commercially available Tak...

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Detalles Bibliográficos
Autores principales: Franco, Francesca, Meninno, Sara, Overgaard, Jacob, Rossi, Sergio, Benaglia, Maurizio, Lattanzi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490835/
https://www.ncbi.nlm.nih.gov/pubmed/35687515
http://dx.doi.org/10.1021/acs.orglett.2c01589

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