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Brønsted Acid Catalyzed (4 + 2) Cyclocondensation of 3-Substituted Indoles with Donor–Acceptor Cyclopropanes
[Image: see text] Acylcyclopropanes are employed as useful donor–acceptor cyclopropanes that undergo formal (4 + 2) cyclocondensation with N-unprotected 3-substituted indoles in the presence of a Brønsted acid catalyst. The reaction involves the simultaneous alkylation of both the N and C-2 position...
Autores principales: | Ortega, Alesandere, Uria, Uxue, Tejero, Tomás, Prieto, Liher, Reyes, Efraim, Merino, Pedro, Vicario, Jose L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490874/ https://www.ncbi.nlm.nih.gov/pubmed/33689377 http://dx.doi.org/10.1021/acs.orglett.1c00470 |
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