Pregabalin mitigates microglial activation and neuronal injury by inhibiting HMGB1 signaling pathway in radiation-induced brain injury

BACKGROUND: Radiation-induced brain injury (RIBI) is the most serious complication of radiotherapy in patients with head and neck tumors, which seriously affects the quality of life. Currently, there is no effective treatment for patients with RIBI, and identifying new treatment that targets the pat...

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Detalles Bibliográficos
Autores principales: Zhang, Zhan, Jiang, Jingru, He, Yong, Cai, Jinhua, Xie, Jiatian, Wu, Minyi, Xing, Mengdan, Zhang, Zhenzhen, Chang, Haocai, Yu, Pei, Chen, Siqi, Yang, Yuhua, Shi, Zhongshan, Liu, Qiang, Sun, Haohui, He, Baixuan, Zeng, Junbo, Huang, Jialin, Chen, Jiongxue, Li, Honghong, Li, Yi, Lin, Wei-Jye, Tang, Yamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490947/
https://www.ncbi.nlm.nih.gov/pubmed/36131309
http://dx.doi.org/10.1186/s12974-022-02596-7

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