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Genomics and epigenetics guided identification of tissue-specific genomic safe harbors

BACKGROUND: Genomic safe harbors are regions of the genome that can maintain transgene expression without disrupting the function of host cells. Genomic safe harbors play an increasingly important role in improving the efficiency and safety of genome engineering. However, limited safe harbors have b...

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Detalles Bibliográficos
Autores principales:	Shrestha, Dewan, Bag, Aishee, Wu, Ruiqiong, Zhang, Yeting, Tang, Xing, Qi, Qian, Xing, Jinchuan, Cheng, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490961/ https://www.ncbi.nlm.nih.gov/pubmed/36131352 http://dx.doi.org/10.1186/s13059-022-02770-3

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