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The N-terminal substrate specificity of the SurE peptide cyclase
SurE is a standalone peptide cyclase essential for the production of surugamide antibiotics. Although SurE catalyses the cyclisation of varied nonribosomal peptides in vivo, its substrate specificity is poorly understood. To address this issue, an on-resin SurE cyclisation assay was developed and in...
Autores principales: | Fazal, Asif, Wheeler, Jake, Webb, Michael E., Seipke, Ryan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491159/ https://www.ncbi.nlm.nih.gov/pubmed/36062889 http://dx.doi.org/10.1039/d2ob01061e |
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