Distinct core glycan and O-glycoform utilization of SARS-CoV-2 Omicron variant Spike protein RBD revealed by top-down mass spectrometry

The SARS-CoV-2 Omicron (B.1.1.529) variant possesses numerous spike (S) mutations particularly in the S receptor-binding domain (S-RBD) that significantly improve transmissibility and evasion of neutralizing antibodies. But exactly how the mutations in the Omicron variant enhance viral escape from i...

Descripción completa

Detalles Bibliográficos
Autores principales: Roberts, David S., Mann, Morgan, Li, Brad H., Kim, Donguk, Braiser, Allan R., Jin, Song, Ge, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491206/
https://www.ncbi.nlm.nih.gov/pubmed/36320702
http://dx.doi.org/10.1039/d2sc02132c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491206/
https://www.ncbi.nlm.nih.gov/pubmed/36320702
http://dx.doi.org/10.1039/d2sc02132c

Ejemplares similares