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Distinct core glycan and O-glycoform utilization of SARS-CoV-2 Omicron variant Spike protein RBD revealed by top-down mass spectrometry

The SARS-CoV-2 Omicron (B.1.1.529) variant possesses numerous spike (S) mutations particularly in the S receptor-binding domain (S-RBD) that significantly improve transmissibility and evasion of neutralizing antibodies. But exactly how the mutations in the Omicron variant enhance viral escape from i...

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Detalles Bibliográficos
Autores principales:	Roberts, David S., Mann, Morgan, Li, Brad H., Kim, Donguk, Braiser, Allan R., Jin, Song, Ge, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491206/ https://www.ncbi.nlm.nih.gov/pubmed/36320702 http://dx.doi.org/10.1039/d2sc02132c

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