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Motif-based zwitterionic peptides impact their structure and immunogenicity

The linkage of zwitterionic peptides containing alternating glutamic acid (E) and lysine (K) amino acids exhibits protective effects on protein drugs due to their high hydration capacity. Previously, short EK peptides covering the surface of a protein drug showed significant protective effects and l...

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Detalles Bibliográficos
Autores principales: McMullen, Patrick, Qiao, Qi, Luozhong, Sijin, Cai, Lirong, Fang, Liang, Shao, Qing, Jiang, Shaoyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491220/
https://www.ncbi.nlm.nih.gov/pubmed/36320710
http://dx.doi.org/10.1039/d2sc03519g