Cargando…

Deep RNA sequencing of intensive care unit patients with COVID-19

COVID-19 has impacted millions of patients across the world. Molecular testing occurring now identifies the presence of the virus at the sampling site: nasopharynx, nares, or oral cavity. RNA sequencing has the potential to establish both the presence of the virus and define the host’s response in C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fredericks, Alger M., Jentzsch, Maximilian S., Cioffi, William G., Cohen, Maya, Fairbrother, William G., Gandhi, Shivam J., Harrington, Elizabeth O., Nau, Gerard J., Reichner, Jonathan S., Ventetuolo, Corey E., Levy, Mitchell M., Ayala, Alfred, Monaghan, Sean F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491252/ https://www.ncbi.nlm.nih.gov/pubmed/36130991 http://dx.doi.org/10.1038/s41598-022-20139-1

Ejemplares similares

Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations
por: Fredericks, Alger M., et al.
Publicado: (2022)

RNA-Binding Proteins: Splicing Factors and Disease
por: Fredericks, Alger M., et al.
Publicado: (2015)

Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness
por: Monaghan, Sean F., et al.
Publicado: (2018)

Soluble programmed cell death receptor-1 (sPD-1): a potential biomarker with anti-inflammatory properties in human and experimental acute respiratory distress syndrome (ARDS)
por: Monaghan, Sean F., et al.
Publicado: (2016)

Application of single cell multiomics points to changes in chromatin accessibility near calcitonin receptor like receptor and a possible role for adrenomedullin in the post-shock lung
por: Armstead, Brandon E., et al.
Publicado: (2023)

Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern
por: Heffernan, Daithi S, et al.
Publicado: (2012)

Neutrophils from critically ill septic patients mediate profound loss of endothelial barrier integrity
por: Fox, Elizabeth D, et al.
Publicado: (2013)

Hereditary cancer genes are highly susceptible to splicing mutations
por: Rhine, Christy L., et al.
Publicado: (2018)

Hemorrhagic shock and fluid dynamics
por: Cohen, Maya, et al.
Publicado: (2021)

Prime Time for Proteomics in Pulmonary Arterial Hypertension Risk Assessment?
por: Singh, Navneet, et al.
Publicado: (2022)

Another Piece in the Estrogen Puzzle of Pulmonary Hypertension
por: Al-Naamani, Nadine, et al.
Publicado: (2020)

Efficient Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) from Exhaled Breath
por: Duan, Chaorui, et al.
Publicado: (2021)

Blood Serum Alpha Fetoprotein Enhancer Binding Protein, a Tumor Suppressor, Decreases in Chronic HBV Hepatitis Patients as Hepatocellular Cancer Appears
por: Riggins, James N., et al.
Publicado: (2010)

B and T lymphocyte attenuator expression on CD4(+) T-cells associates with sepsis and subsequent infections in ICU patients
por: Shubin, Nicholas J, et al.
Publicado: (2013)

Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients
por: Dickinson, Catherine M., et al.
Publicado: (2018)

Commercial human pulmonary artery endothelial cells have in‐vitro behavior that varies by sex
por: Cox‐Flaherty, Katherine, et al.
Publicado: (2022)

Re: Karin Welén, Ebba Rosendal, Magnus Gisslén, et al. A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data. Eur Urol. 2022;81:285–93: Positive Effects of Enzalutamide for Hospitalized COVID-19 Patients
por: Wambier, Carlos G., et al.
Publicado: (2022)

Novel Role for PD-1:PD-L1 as Mediator of Pulmonary Vascular Endothelial Cell Functions in Pathogenesis of Indirect ARDS in Mice
por: Lomas-Neira, Joanne, et al.
Publicado: (2018)

Systolic Strain by Speckle-Tracking Echocardiography Is a Feasible and Sensitive Measure of Right Ventricular Dysfunction in Acute Respiratory Failure Patients on Mechanical Ventilation
por: Simmons, James, et al.
Publicado: (2022)

Neutrophil Integrins and Matrix Ligands and NET Release
por: O’Brien, Xian M., et al.
Publicado: (2016)

Lymphopenia following pancreaticoduodenectomy is associated with pancreatic fistula formation
por: Cohen, Joshua T., et al.
Publicado: (2021)

Machine learning to predict hemorrhage and thrombosis during extracorporeal membrane oxygenation
por: Abbasi, Adeel, et al.
Publicado: (2020)

Relational Memory: A Daytime Nap Facilitates the Abstraction of General Concepts
por: Lau, Hiuyan, et al.
Publicado: (2011)

Delayed Onset of a Daytime Nap Facilitates Retention of Declarative Memory
por: Alger, Sara E., et al.
Publicado: (2010)

Complication of antiquated tuberculosis treatment
por: Husta, Bryan, et al.
Publicado: (2014)

Single Nucleotide Polymorphism–Based Validation of Exonic Splicing Enhancers
por: Fairbrother, William G, et al.
Publicado: (2004)

Hotspot exons are common targets of splicing perturbations
por: Glidden, David T., et al.
Publicado: (2021)

Soluble programmed cell death protein-1 and programmed cell death ligand-1 in sepsis
por: Banerjee, Debasree, et al.
Publicado: (2018)

Pulmonary Vascular Dilatation Detected by Automated Transcranial Doppler in COVID-19 Pneumonia
por: Reynolds, Alexandra S., et al.
Publicado: (2020)

Reply to Cherian et al.: Positive Bubble Study in Severe COVID-19 Indicates the Development of Anatomical Intrapulmonary Shunts in Response to Microvascular Occlusion
por: Reynolds, Alexandra S., et al.
Publicado: (2021)

Reply to Chiang and Gupta and to Swenson et al.
por: Reynolds, Alexandra S., et al.
Publicado: (2021)

Mapping and analysis of laws influencing built environments for walking and cycling in Australia
por: Nau, Tracy, et al.
Publicado: (2023)

A Case of Plastic Surgery
por: Fredericks, A. G.
Publicado: (1883)

Large-scale analysis of branchpoint usage across species and cell lines
por: Taggart, Allison J., et al.
Publicado: (2017)

Mutational bias and the protein code shape the evolution of splicing enhancers
por: Rong, Stephen, et al.
Publicado: (2020)

Knowledge and risk perception of sexually transmitted infections and relevant health care services among high school students in the Platfontein San community, Northern Cape Province, South Africa
por: Nyasulu, Peter, et al.
Publicado: (2018)

Describing Directional Cell Migration with a Characteristic Directionality Time
por: Loosley, Alex J., et al.
Publicado: (2015)

Cardiac index is associated with oxygenation in COVID-19 acute respiratory distress syndrome
por: Poor, Hooman D., et al.
Publicado: (2021)

Quadruped Gait and Regulation of Apoptotic Factors in Tibiofemoral Joints following Intra-Articular rhPRG4 Injection in Prg4 Null Mice
por: Yang, Daniel S., et al.
Publicado: (2022)

Mechanosensitive traction force generation is regulated by the neutrophil activation state
por: Witt, Hadley, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0f7qc172t678b81h3163ejh5ed