Clinical Implementation of Combined Monogenic and Polygenic Risk Disclosure for Coronary Artery Disease

BACKGROUND: State-of-the-art genetic risk interpretation for a common complex disease such as coronary artery disease (CAD) requires assessment for both monogenic variants—such as those related to familial hypercholesterolemia—as well as the cumulative impact of many common variants, as quantified b...

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Detalles Bibliográficos
Autores principales: Maamari, Dimitri J., Brockman, Deanna G., Aragam, Krishna, Pelletier, Renée C., Folkerts, Emma, Neben, Cynthia L., Okumura, Sydney, Hull, Leland E., Philippakis, Anthony A., Natarajan, Pradeep, Ellinor, Patrick T., Ng, Kenney, Zhou, Alicia Y., Khera, Amit V., Fahed, Akl C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491373/
https://www.ncbi.nlm.nih.gov/pubmed/36147540
http://dx.doi.org/10.1016/j.jacadv.2022.100068

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