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Investigation of cell signalings and therapeutic targets in PTPRK-RSPO3 fusion-positive colorectal cancer
INTRODUCTION: Colorectal cancer (CRC) is one of the most deadly and common diseases in the world, accounting for over 881,000 casualties in 2018. The PTPRK-RSPO3 (P:R) fusion is a structural variation in CRC and well known for its ability to activate WNT signaling and tumorigenesis. However, till no...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491571/ https://www.ncbi.nlm.nih.gov/pubmed/36129915 http://dx.doi.org/10.1371/journal.pone.0274555 |