Proteogenomic analysis of cancer aneuploidy and normal tissues reveals divergent modes of gene regulation across cellular pathways

How cells control gene expression is a fundamental question. The relative contribution of protein-level and RNA-level regulation to this process remains unclear. Here, we perform a proteogenomic analysis of tumors and untransformed cells containing somatic copy number alterations (SCNAs). By reveali...

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Detalles Bibliográficos
Autores principales: Cheng, Pan, Zhao, Xin, Katsnelson, Lizabeth, Camacho-Hernandez, Elaine M, Mermerian, Angela, Mays, Joseph C, Lippman, Scott M, Rosales-Alvarez, Reyna Edith, Moya, Raquel, Shwetar, Jasmine, Grun, Dominic, Fenyo, David, Davoli, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491860/
https://www.ncbi.nlm.nih.gov/pubmed/36129397
http://dx.doi.org/10.7554/eLife.75227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491860/
https://www.ncbi.nlm.nih.gov/pubmed/36129397
http://dx.doi.org/10.7554/eLife.75227

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