Cargando…

Proteogenomic analysis of cancer aneuploidy and normal tissues reveals divergent modes of gene regulation across cellular pathways

How cells control gene expression is a fundamental question. The relative contribution of protein-level and RNA-level regulation to this process remains unclear. Here, we perform a proteogenomic analysis of tumors and untransformed cells containing somatic copy number alterations (SCNAs). By reveali...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Pan, Zhao, Xin, Katsnelson, Lizabeth, Camacho-Hernandez, Elaine M, Mermerian, Angela, Mays, Joseph C, Lippman, Scott M, Rosales-Alvarez, Reyna Edith, Moya, Raquel, Shwetar, Jasmine, Grun, Dominic, Fenyo, David, Davoli, Teresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491860/ https://www.ncbi.nlm.nih.gov/pubmed/36129397 http://dx.doi.org/10.7554/eLife.75227

Ejemplares similares

Proteogenomics unveils mechanistic insights to precision oncology
por: Dou, Yongchao, et al.
Publicado: (2023)

Proteogenomics Reveal the Overexpression of HLA-I in Cancer
por: Wang, Ying, et al.
Publicado: (2023)

Proteogenomic characterization of cholangiocarcinoma
por: Deng, Mengjie, et al.
Publicado: (2023)

Pan-cancer proteogenomic analysis reveals long and circular noncoding RNAs encoding peptides
por: Othoum, Ghofran, et al.
Publicado: (2020)

Exploring the Immunogenicity of Noncanonical HLA-I Tumor Ligands Identified through Proteogenomics
por: Lozano-Rabella, Maria, et al.
Publicado: (2023)

BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer
por: Weaver, Robbyn L, et al.
Publicado: (2016)

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy
por: Springer, Simeon U, et al.
Publicado: (2018)

Contribution of BubR1 to oxidative stress-induced aneuploidy in p53-deficient cells
por: Ikawa-Yoshida, Ayae, et al.
Publicado: (2013)

Correction: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy
por: Springer, Simeon U, et al.
Publicado: (2018)

Detection of malignant peripheral nerve sheath tumors in patients with neurofibromatosis using aneuploidy and mutation identification in plasma
por: Mattox, Austin K, et al.
Publicado: (2022)

VarID2 quantifies gene expression noise dynamics and unveils functional heterogeneity of ageing hematopoietic stem cells
por: Rosales-Alvarez, Reyna Edith, et al.
Publicado: (2023)

High ubiquitin‐specific protease 44 expression induces DNA aneuploidy and provides independent prognostic information in gastric cancer
por: Nishimura, Sho, et al.
Publicado: (2017)

DNA aneuploidy with image cytometry for detecting dysplasia and carcinoma in oral potentially malignant disorders: A prospective diagnostic study
por: Li, Chenxi, et al.
Publicado: (2020)

The Proteogenomic Mapping Tool
por: Sanders, William S, et al.
Publicado: (2011)

The bacterial proteogenomic pipeline
por: Uszkoreit, Julian, et al.
Publicado: (2014)

A community‐based lung cancer rapid tissue donation protocol provides high‐quality drug‐resistant specimens for proteogenomic analyses
por: Boyle, Theresa A., et al.
Publicado: (2019)

Enhanced protein isoform characterization through long-read proteogenomics
por: Miller, Rachel M., et al.
Publicado: (2022)

Proteogenomics connects somatic mutations to signaling in breast cancer
por: Mertins, Philipp, et al.
Publicado: (2016)

Comparative proteogenomic characterization of glioblastoma
por: Asif, Samia, et al.
Publicado: (2019)

Systems proteogenomics for precision oncology
por: Klauschen, Frederick
Publicado: (2019)

Proteogenomics for pediatric brain cancer
por: SIMONIAN, Margaret
Publicado: (2021)

Proteogenomic Analysis of Polymorphisms and Gene Annotation Divergences in Prokaryotes using a Clustered Mass Spectrometry-Friendly Database
por: de Souza, Gustavo A., et al.
Publicado: (2011)

Deep learning integrates histopathology and proteogenomics at a pan-cancer level
por: Wang, Joshua M., et al.
Publicado: (2023)

Challenges in proteogenomics: a comparison of analysis methods with the case study of the DREAM proteogenomics sub-challenge
por: Eicher, Tara, et al.
Publicado: (2019)

Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy
por: Krug, Karsten, et al.
Publicado: (2020)

Proteogenomic analysis of Serratia marcescens using computational subtractive genomics approach
por: D’Souza, Sharon Elaine, et al.
Publicado: (2023)

Proteogenomic links to human metabolic diseases
por: Koprulu, Mine, et al.
Publicado: (2023)

Microscaled proteogenomic methods for precision oncology
por: Satpathy, Shankha, et al.
Publicado: (2020)

Proteogenomic analysis of pancreatic cancer subtypes
por: Kafita, Doris, et al.
Publicado: (2021)

S189: PROTEOGENOMIC LANDSCAPE OF MULTIPLE MYELOMA
por: Ramberger, Evelyn, et al.
Publicado: (2023)

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts
por: Huang, Kuan-lin, et al.
Publicado: (2017)

Quantitative Proteogenomic Characterization of Inflamed Murine Colon Tissue Using an Integrated Discovery, Verification, and Validation Proteogenomic Workflow
por: Rajczewski, Andrew T., et al.
Publicado: (2022)

Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts
por: Huang, Kuan-lin, et al.
Publicado: (2017)

Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer
por: Chowdhury, Shrabanti, et al.
Publicado: (2023)

Immune Checkpoint Inhibitors in the Treatment of Breast Cancer Brain Metastases
por: Schlam, Ilana, et al.
Publicado: (2022)

Proteogenomic convergence for understanding cancer pathways and networks
por: Boja, Emily S, et al.
Publicado: (2014)

The influence of transcript assembly on the proteogenomics discovery of microproteins
por: Ma, Jiao, et al.
Publicado: (2018)

Proteogenomic characterization and integrative analysis of glioblastoma multiforme
por: Song, Ying-Chun, et al.
Publicado: (2017)

Proteogenomic landscape of squamous cell lung cancer
por: Stewart, Paul A., et al.
Publicado: (2019)

Breast cancer quantitative proteome and proteogenomic landscape
por: Johansson, Henrik J., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_323gfcmmphh4s2pvmngaa6u4p0