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Sustained vascular contractile response induced by an R- and S-epimer of the ergot alkaloid ergocristine and attenuation by a noncompetitive antagonist
Vasoconstriction is a known effect associated with ergot alkaloid consumption. The vascular contractile responses are often sustained for an extended period after exposure. Ergot alkaloids exist in two molecular configurations, the C-8-(R)-isomer (R-epimer) and the C-8-(S)-isomer (S-epimer). The sus...
Autores principales: | Cherewyk, Jensen E, Parker, Sarah E, Blakley, Barry R, Al-Dissi, Ahmad N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492154/ https://www.ncbi.nlm.nih.gov/pubmed/35775420 http://dx.doi.org/10.1093/jas/skac235 |
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