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Cytokine Mixtures Mimicking the Local Milieu in Patients with Inflammatory Bowel Disease Impact Phenotype and Function of Mesenchymal Stromal Cells

Locally applied mesenchymal stromal cells (MSCs) have the capacity to promote the healing of perianal fistulas in Crohn’s disease (CD) and are under clinical development for the treatment of proctitis in ulcerative colitis (UC). Despite these clinical advances, the mechanism of action of local MSC t...

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Detalles Bibliográficos
Autores principales:	Barnhoorn, Marieke C, van der Meulen-de Jong, Andrea E, Schrama, Ellen C L M, Plug, Leonie G, Verspaget, Hein W, Fibbe, Willem E, van Pel, Melissa, Hawinkels, Lukas J A C, Schepers, Koen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Cell-Based Drug Development, Screening, and Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492159/ https://www.ncbi.nlm.nih.gov/pubmed/35984079 http://dx.doi.org/10.1093/stcltm/szac054

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