METTL14 Regulates Osteogenesis of Bone Marrow Mesenchymal Stem Cells via Inducing Autophagy Through m(6)A/IGF2BPs/Beclin-1 Signal Axis

The development of osteoporosis is often accompanied by autophagy disturbance, which also causes new osteoblast defects from bone marrow mesenchymal stem cells (BMSCs). However, the underlying molecular mechanisms are still not fully understood. Methyltransferase-like 14 (METTL14) is the main enzyme...

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Detalles Bibliográficos
Autores principales: He, Mingyu, Lei, Hong, He, Xiaoqi, Liu, Ying, Wang, Ao, Ren, Zijing, Liu, Xiaoyan, Yan, Gege, Wang, Wenbo, Wang, Yang, Li, Guanghui, Wang, Tong, Pu, Jiaying, Shen, Zhihua, Wang, Yanquan, Xie, Jiajie, Du, Weijie, Yuan, Ye, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492283/
https://www.ncbi.nlm.nih.gov/pubmed/35980318
http://dx.doi.org/10.1093/stcltm/szac049

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