Cargando…

EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis

OBJECTIVE: This study was designed to explore the role and mechanism of eukaryotic initiation factor 3C (EIF3C) in the proliferation and apoptosis of lung cancer cells. METHODS: EIF3C expression in clinic lung cancer tissues was detected by immunohistochemistry assay. Cell transfection with lentivir...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, Xiaoli, Hou, Lanlan, Zhang, Huijuan, Chen, Zhiping, Liu, Zhanyu, Gong, Junjie, Tang, Zhixian, Hu, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492341/ https://www.ncbi.nlm.nih.gov/pubmed/36157221 http://dx.doi.org/10.1155/2022/9464094

Ejemplares similares

Upregulation of HSPA1A/HSPA1B/HSPA7 and Downregulation of HSPA9 Were Related to Poor Survival in Colon Cancer
por: Guan, Yufeng, et al.
Publicado: (2021)

LMNB1 targets FOXD1 to promote progression of prostate cancer
por: Huang, Yuanshe, et al.
Publicado: (2023)

Silencing LMNB1 Contributes to the Suppression of Lung Adenocarcinoma Development
por: Tang, Dan, et al.
Publicado: (2021)

Screening and identification of LMNB1 and DLGAP5, two key biomarkers in gliomas
por: Zhou, Ding, et al.
Publicado: (2021)

LMNB1‐related autosomal‐dominant leukodystrophy: Clinical and radiological course
por: Finnsson, Johannes, et al.
Publicado: (2015)

Is LMNB1 a Susceptibility Gene for Neural Tube Defects in Humans?
por: Robinson, Alexis, et al.
Publicado: (2013)

Glucose metabolism in the brain in LMNB1‐related autosomal dominant leukodystrophy
por: Finnsson, Johannes, et al.
Publicado: (2018)

Plasmacytoma variant translocation 1 stabilized by EIF4A3 promoted malignant biological behaviors of lung adenocarcinoma by generating circular RNA LMNB2
por: Qiu, Minglian, et al.
Publicado: (2022)

Duplication and deletion upstream of LMNB1 in autosomal dominant adult-onset leukodystrophy
por: Mezaki, Naomi, et al.
Publicado: (2018)

CircPTPRA promotes the progression of pancreatic ductal adenocarcinoma via the miR‐140‐5p/LMNB1 axis
por: Fu, Wen, et al.
Publicado: (2023)

HSPA4 Knockdown Retarded Progression and Development of Colorectal Cancer
por: Zhang, Mingliang, et al.
Publicado: (2021)

LMNB1 Duplication-Mediated Autosomal Dominant Adult-Onset Leukodystrophy in an Indian Family
por: Bijarnia-Mahay, Sunita, et al.
Publicado: (2021)

HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease
por: Dong, Yeqing, et al.
Publicado: (2022)

Functional redundancy of HSPA1, HSPA2 and other HSPA proteins in non-small cell lung carcinoma (NSCLC); an implication for NSCLC treatment
por: Sojka, Damian Robert, et al.
Publicado: (2019)

Comprehensive analysis of expression and prognosis for LMNB family genes in human sarcoma
por: Wu, Gen, et al.
Publicado: (2022)

HSPA5 Inhibitor Meliorate DSS-Induced Colitis through HSPA1A/CHIP
por: Gao, Fei, et al.
Publicado: (2022)

CircLMNB1 promotes colorectal cancer by regulating cell proliferation, apoptosis and epithelial-mesenchymal transition
por: He, Chunping, et al.
Publicado: (2019)

Knockdown of LMNB1 Inhibits the Proliferation of Lung Adenocarcinoma Cells by Inducing DNA Damage and Cell Senescence
por: Li, Jiangbo, et al.
Publicado: (2022)

Retracted: HSPA5 Inhibitor Meliorate DSS-Induced Colitis through HSPA1A/CHIP
por: Markers, Disease
Publicado: (2023)

LMNB1-Related Adult-Onset Autosomal Dominant Leukodystrophy Presenting as Movement Disorder: A Case Report and Review of the Literature
por: Zhang, Yanyan, et al.
Publicado: (2019)

Heat-Induced Proteotoxic Stress Response in Placenta-Derived Stem Cells (PDSCs) Is Mediated through HSPA1A and HSPA1B with a Potential Higher Role for HSPA1B
por: Alharbi, Bothina Mohammed, et al.
Publicado: (2022)

HSPA1A, HSPA1L and TRAP1 heat shock genes may be associated with prognosis in ovarian epithelial cancer
por: De Andrade, Warne Pedro, et al.
Publicado: (2020)

LMNB2 promotes the progression of colorectal cancer by silencing p21 expression
por: Dong, Chen-Hua, et al.
Publicado: (2021)

miR-122 Inhibits Hepatocarcinoma Cell Progression by Targeting LMNB2
por: Li, Xiao-Na, et al.
Publicado: (2020)

Inhibition of DNAJC12 Inhibited Tumorigenesis of Rectal Cancer via Downregulating HSPA4 Expression
por: Sun, Qi, et al.
Publicado: (2022)

Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity
por: Wu, Chung-Yin, et al.
Publicado: (2011)

Analysis of LMNB1 Duplications in Autosomal Dominant Leukodystrophy Provides Insights into Duplication Mechanisms and Allele-Specific Expression
por: Giorgio, Elisa, et al.
Publicado: (2013)

Differential expression of HSPA1 and HSPA2 proteins in human tissues; tissue microarray-based immunohistochemical study
por: Scieglinska, Dorota, et al.
Publicado: (2011)

Roles of eIF3m in the tumorigenesis of triple negative breast cancer
por: Han, Wei, et al.
Publicado: (2020)

Polymorphisms of heat shock protein 70 genes (HSPA1A, HSPA1B and HSPA1L) and susceptibility of noise-induced hearing loss in a Chinese population: A case-control study
por: Li, Yanhong, et al.
Publicado: (2017)

Upregulation of Heat Shock Proteins (HSPA12A, HSP90B1, HSPA4, HSPA5 and HSPA6) in Tumour Tissues Is Associated with Poor Outcomes from HBV-Related Early-Stage Hepatocellular Carcinoma
por: Yang, Zongguo, et al.
Publicado: (2015)

A Rare Mutation in LMNB2 Associated with Lipodystrophy Drives Premature Cell Senescence
por: Varlet, Alice-Anaïs, et al.
Publicado: (2021)

Retracted: Inhibition of DNAJC12 Inhibited Tumorigenesis of Rectal Cancer via Downregulating HSPA4 Expression
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Correspondence: On the enzymology and significance of HSPA1 lysine methylation
por: Jakobsson, Magnus E., et al.
Publicado: (2016)

Crystal Structures of the ATPase Domains of Four Human Hsp70 Isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
por: Wisniewska, Magdalena, et al.
Publicado: (2010)

Pan-cancer analysis identifies LMNB1 as a target to redress Th1/Th2 imbalance and enhance PARP inhibitor response in human cancers
por: Qin, Haixiang, et al.
Publicado: (2022)

Targeting HSPA1A in ARID2-deficient lung adenocarcinoma
por: Wang, Xue, et al.
Publicado: (2021)

An LMNB1 Duplication Caused Adult-Onset Autosomal Dominant Leukodystrophy in Chinese Family: Clinical Manifestations, Neuroradiology and Genetic Diagnosis
por: Dai, Yi, et al.
Publicado: (2017)

Genome sequencing reveals novel noncoding variants in PLA2G6 and LMNB1 causing progressive neurologic disease
por: Borja, Nicholas, et al.
Publicado: (2022)

ER Stress–Related Genes EIF2AK3, HSPA5, and DDIT3 Polymorphisms are Associated With Risk of Lung Cancer
por: Liu, Yongshi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_k1ualcoh6ra9r6ve2lu6trcjju