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Atractylenolide III Attenuates Apoptosis in H9c2 Cells by Inhibiting Endoplasmic Reticulum Stress through the GRP78/PERK/CHOP Signaling Pathway

The objective of this study was to determine the effect of atractylenolide III (ATL-III) on endoplasmic reticulum stress (ERS) injury, H9c2 cardiomyocyte apoptosis induced by tunicamycin (TM), and the GRP78/PERK/CHOP signaling pathway. Molecular docking was applied to predict the binding affinity of...

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Detalles Bibliográficos
Autores principales: Zuo, Meng-yu, Tang, Tong-juan, Wang, Xiang, Gu, Jin-fan, Wang, Liang, Chen, Jian, Yao, Juan, Li, Xiang-yang, Zhou, Peng, Huang, Jin-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492373/
https://www.ncbi.nlm.nih.gov/pubmed/36159560
http://dx.doi.org/10.1155/2022/1149231