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Detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the UK: A cause for alarm

The re-emergence of polio in the UK reminds us that the global threat of polio remains. Viruses know no bounds or borders. COVID-19, Monkeypox, and polio are evidence of this. Poliomyelitis was once the leading cause of death and paralysis in the UK and globally. With the introduction of vaccines du...

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Autores principales: Kamran, Ateeba, Salman, Maira, Siddiqui, Rida, Shabbir, Noor Zehra, Rohail, Samia, Sukaina, Mahnoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492381/
https://www.ncbi.nlm.nih.gov/pubmed/36164645
http://dx.doi.org/10.1016/j.amsu.2022.104773
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author Kamran, Ateeba
Salman, Maira
Siddiqui, Rida
Shabbir, Noor Zehra
Rohail, Samia
Sukaina, Mahnoor
author_facet Kamran, Ateeba
Salman, Maira
Siddiqui, Rida
Shabbir, Noor Zehra
Rohail, Samia
Sukaina, Mahnoor
author_sort Kamran, Ateeba
collection PubMed
description The re-emergence of polio in the UK reminds us that the global threat of polio remains. Viruses know no bounds or borders. COVID-19, Monkeypox, and polio are evidence of this. Poliomyelitis was once the leading cause of death and paralysis in the UK and globally. With the introduction of vaccines during the 1950s–1960s, polio was eradicated from most developed countries, including the UK. The last case of wild polio was in 1984, and the UK was polio-free in 2003. The recent detection of vaccine-derived poliovirus type 2 in London sewage samples is alarming. Routine inoculations were adversely affected due to COVID-19, and UK's wastewater monitoring program was suspended due to economic restrictions. The UK faces several challenges with the burden of COVID-19, Monkeypox, and the return of polio could further burden the already pandemic-stricken healthcare system. To prevent further epidemics in the UK, wastewater sampling remains crucial in evaluating, searching, and eradicating the spread of poliovirus. Further epidemiological surveillance in adjacent areas to the Beckton plant is crucial to filling any gaps in understanding the outbreak's extent and guiding the initiation of appropriate and timely public health measures. The importance of vaccination in unvaccinated or incompletely vaccinated individuals cannot be overstated, especially in areas where vaccination rates are low. The risk of polio remains globally until its complete eradication from endemic countries. Until elimination, a global effort should be made to minimize the risk and the consequent spread of poliovirus by maintaining strong population immunity levels through high vaccination coverage.
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spelling pubmed-94923812022-09-22 Detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the UK: A cause for alarm Kamran, Ateeba Salman, Maira Siddiqui, Rida Shabbir, Noor Zehra Rohail, Samia Sukaina, Mahnoor Ann Med Surg (Lond) Commentary The re-emergence of polio in the UK reminds us that the global threat of polio remains. Viruses know no bounds or borders. COVID-19, Monkeypox, and polio are evidence of this. Poliomyelitis was once the leading cause of death and paralysis in the UK and globally. With the introduction of vaccines during the 1950s–1960s, polio was eradicated from most developed countries, including the UK. The last case of wild polio was in 1984, and the UK was polio-free in 2003. The recent detection of vaccine-derived poliovirus type 2 in London sewage samples is alarming. Routine inoculations were adversely affected due to COVID-19, and UK's wastewater monitoring program was suspended due to economic restrictions. The UK faces several challenges with the burden of COVID-19, Monkeypox, and the return of polio could further burden the already pandemic-stricken healthcare system. To prevent further epidemics in the UK, wastewater sampling remains crucial in evaluating, searching, and eradicating the spread of poliovirus. Further epidemiological surveillance in adjacent areas to the Beckton plant is crucial to filling any gaps in understanding the outbreak's extent and guiding the initiation of appropriate and timely public health measures. The importance of vaccination in unvaccinated or incompletely vaccinated individuals cannot be overstated, especially in areas where vaccination rates are low. The risk of polio remains globally until its complete eradication from endemic countries. Until elimination, a global effort should be made to minimize the risk and the consequent spread of poliovirus by maintaining strong population immunity levels through high vaccination coverage. Elsevier 2022-09-22 /pmc/articles/PMC9492381/ /pubmed/36164645 http://dx.doi.org/10.1016/j.amsu.2022.104773 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Commentary
Kamran, Ateeba
Salman, Maira
Siddiqui, Rida
Shabbir, Noor Zehra
Rohail, Samia
Sukaina, Mahnoor
Detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the UK: A cause for alarm
title Detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the UK: A cause for alarm
title_full Detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the UK: A cause for alarm
title_fullStr Detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the UK: A cause for alarm
title_full_unstemmed Detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the UK: A cause for alarm
title_short Detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the UK: A cause for alarm
title_sort detection of vaccine-derived poliovirus type 2 amid the burden of infectious diseases in the uk: a cause for alarm
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492381/
https://www.ncbi.nlm.nih.gov/pubmed/36164645
http://dx.doi.org/10.1016/j.amsu.2022.104773
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