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Clopidogrel-induced Eosinophilia with Hypercalcemia

There are few cases describing the association of eosinophilia with hypercalcemia, and drug-induced eosinophilia with hypercalcemia has not been reported. A 74-year-old man had been diagnosed with asthma 4 months earlier. He was admitted due to eosinophilia with hypercalcemia. Chest computed tomogra...

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Autores principales: Yamada, Kazuhiro, Asai, Kazuhisa, Yanagimoto, Misaki, Sone, Risa, Inazu, Satsuki, Mizutani, Ryo, Kadotani, Hideaki, Watanabe, Tetsuya, Tochino, Yoshihiro, Kawaguchi, Tomoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492498/
https://www.ncbi.nlm.nih.gov/pubmed/35135910
http://dx.doi.org/10.2169/internalmedicine.7830-21
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author Yamada, Kazuhiro
Asai, Kazuhisa
Yanagimoto, Misaki
Sone, Risa
Inazu, Satsuki
Mizutani, Ryo
Kadotani, Hideaki
Watanabe, Tetsuya
Tochino, Yoshihiro
Kawaguchi, Tomoya
author_facet Yamada, Kazuhiro
Asai, Kazuhisa
Yanagimoto, Misaki
Sone, Risa
Inazu, Satsuki
Mizutani, Ryo
Kadotani, Hideaki
Watanabe, Tetsuya
Tochino, Yoshihiro
Kawaguchi, Tomoya
author_sort Yamada, Kazuhiro
collection PubMed
description There are few cases describing the association of eosinophilia with hypercalcemia, and drug-induced eosinophilia with hypercalcemia has not been reported. A 74-year-old man had been diagnosed with asthma 4 months earlier. He was admitted due to eosinophilia with hypercalcemia. Chest computed tomography showed a nodule in the left lung and mediastinal lymphadenopathy. By obtaining a detailed medical history, clopidogrel was suspected as the prime cause of eosinophilia. After the discontinuation of clopidogrel, the eosinophilia with hypercalcemia, lung nodule and mediastinal lymphadenopathy improved. Clopidogrel-induced eosinophilia can potentially cause hypercalcemia. Obtaining a detailed clinical history is important in diagnosing the cause of eosinophilia.
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spelling pubmed-94924982022-10-04 Clopidogrel-induced Eosinophilia with Hypercalcemia Yamada, Kazuhiro Asai, Kazuhisa Yanagimoto, Misaki Sone, Risa Inazu, Satsuki Mizutani, Ryo Kadotani, Hideaki Watanabe, Tetsuya Tochino, Yoshihiro Kawaguchi, Tomoya Intern Med Case Report There are few cases describing the association of eosinophilia with hypercalcemia, and drug-induced eosinophilia with hypercalcemia has not been reported. A 74-year-old man had been diagnosed with asthma 4 months earlier. He was admitted due to eosinophilia with hypercalcemia. Chest computed tomography showed a nodule in the left lung and mediastinal lymphadenopathy. By obtaining a detailed medical history, clopidogrel was suspected as the prime cause of eosinophilia. After the discontinuation of clopidogrel, the eosinophilia with hypercalcemia, lung nodule and mediastinal lymphadenopathy improved. Clopidogrel-induced eosinophilia can potentially cause hypercalcemia. Obtaining a detailed clinical history is important in diagnosing the cause of eosinophilia. The Japanese Society of Internal Medicine 2022-02-08 2022-09-01 /pmc/articles/PMC9492498/ /pubmed/35135910 http://dx.doi.org/10.2169/internalmedicine.7830-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yamada, Kazuhiro
Asai, Kazuhisa
Yanagimoto, Misaki
Sone, Risa
Inazu, Satsuki
Mizutani, Ryo
Kadotani, Hideaki
Watanabe, Tetsuya
Tochino, Yoshihiro
Kawaguchi, Tomoya
Clopidogrel-induced Eosinophilia with Hypercalcemia
title Clopidogrel-induced Eosinophilia with Hypercalcemia
title_full Clopidogrel-induced Eosinophilia with Hypercalcemia
title_fullStr Clopidogrel-induced Eosinophilia with Hypercalcemia
title_full_unstemmed Clopidogrel-induced Eosinophilia with Hypercalcemia
title_short Clopidogrel-induced Eosinophilia with Hypercalcemia
title_sort clopidogrel-induced eosinophilia with hypercalcemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492498/
https://www.ncbi.nlm.nih.gov/pubmed/35135910
http://dx.doi.org/10.2169/internalmedicine.7830-21
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