Macrophages in obesity are characterised by increased IL-1β response to calcium-sensing receptor signals

OBJECTIVE: Obesity is complicated by inflammatory activation of the innate immune system. Stimulation of the calcium-sensing receptor (CaSR) by extra-cellular calcium ions ([Ca(2+)](ex)) can trigger NLRP3 inflammasome activation and inflammation. We hypothesised, that this mechanism might contribute...

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Detalles Bibliográficos
Autores principales: Thrum, Stephan, Sommer, Miriam, Raulien, Nora, Gericke, Martin, Massier, Lucas, Kovacs, Peter, Krasselt, Marco, Landgraf, Kathrin, Körner, Antje, Dietrich, Arne, Blüher, Matthias, Rossol, Manuela, Wagner, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492543/
https://www.ncbi.nlm.nih.gov/pubmed/35931812
http://dx.doi.org/10.1038/s41366-022-01135-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492543/
https://www.ncbi.nlm.nih.gov/pubmed/35931812
http://dx.doi.org/10.1038/s41366-022-01135-x

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