The mechanism of RNA capping by SARS-CoV-2

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The RNA genome of SARS-CoV-2 contains a 5′ cap that facilitates the translation of viral proteins, protection from exonucleases and evasion of the host immune response(1–4). How this cap is made in SARS-CoV-2 is not completely understood. Here we reconstitute the N7- and 2′-O-methylated SARS-CoV-2 R...

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Detalles Bibliográficos
Autores principales: Park, Gina J., Osinski, Adam, Hernandez, Genaro, Eitson, Jennifer L., Majumdar, Abir, Tonelli, Marco, Henzler-Wildman, Katie, Pawłowski, Krzysztof, Chen, Zhe, Li, Yang, Schoggins, John W., Tagliabracci, Vincent S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492545/
https://www.ncbi.nlm.nih.gov/pubmed/35944563
http://dx.doi.org/10.1038/s41586-022-05185-z
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