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Metabolic pathway assembly using docking domains from type I cis-AT polyketide synthases

Engineered metabolic pathways in microbial cell factories often have no natural organization and have challenging flux imbalances, leading to low biocatalytic efficiency. Modular polyketide synthases (PKSs) are multienzyme complexes that synthesize polyketide products via an assembly line thiotempla...

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Detalles Bibliográficos
Autores principales:	Sun, Xixi, Yuan, Yujie, Chen, Qitong, Nie, Shiqi, Guo, Jiaxuan, Ou, Zutian, Huang, Min, Deng, Zixin, Liu, Tiangang, Ma, Tian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492657/ https://www.ncbi.nlm.nih.gov/pubmed/36130947 http://dx.doi.org/10.1038/s41467-022-33272-2

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