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Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation

Dysregulated secretion in neutrophil leukocytes associates with human inflammatory disease. The exocytosis response to triggering stimuli is sequential; gelatinase granules modulate the initiation of the innate immune response, followed by the release of pro-inflammatory azurophilic granules, requir...

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Detalles Bibliográficos
Autores principales: Johnson, Jennifer L., Meneses-Salas, Elsa, Ramadass, Mahalakshmi, Monfregola, Jlenia, Rahman, Farhana, Carvalho Gontijo, Raquel, Kiosses, William B., Pestonjamasp, Kersi, Allen, Dale, Zhang, Jinzhong, Osborne, Douglas G., Zhu, Yanfang Peipei, Wineinger, Nathan, Askari, Kasra, Chen, Danni, Yu, Juan, Henderson, Scott C., Hedrick, Catherine C., Ursini, Matilde Valeria, Grinstein, Sergio, Billadeau, Daniel D., Catz, Sergio D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492659/
https://www.ncbi.nlm.nih.gov/pubmed/36130971
http://dx.doi.org/10.1038/s41467-022-33230-y