Cargando…

Cocaine regulation of Nr4a1 chromatin bivalency and mRNA in male and female mice

Cocaine epigenetically regulates gene expression via changes in histone post-translational modifications (HPTMs). We previously found that the immediate early gene Nr4a1 is epigenetically activated by cocaine in mouse brain reward regions. However, few studies have examined multiple HPTMs at a singl...

Descripción completa

Detalles Bibliográficos
Autores principales: Fischer, Delaney K., Krick, Keegan S., Han, Chloe, Woolf, Morgan T., Heller, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492678/
https://www.ncbi.nlm.nih.gov/pubmed/36130958
http://dx.doi.org/10.1038/s41598-022-19908-9