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Central Pontine Myelinolysis: A Case Report

Central pontine myelinolysis (CPM) classically occurs due to rapid rise in serum osmolarity. Most cases have been associated with a history of chronic alcohol abuse, malnutrition, diuretic abuse, and hyponatremia. The pathological process of CPM starts in the central pons near median raphe and sprea...

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Autores principales: Tiwari, Richa, Kumari, Anju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492751/
https://www.ncbi.nlm.nih.gov/pubmed/36213701
http://dx.doi.org/10.5005/jp-journals-10071-24311
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author Tiwari, Richa
Kumari, Anju
author_facet Tiwari, Richa
Kumari, Anju
author_sort Tiwari, Richa
collection PubMed
description Central pontine myelinolysis (CPM) classically occurs due to rapid rise in serum osmolarity. Most cases have been associated with a history of chronic alcohol abuse, malnutrition, diuretic abuse, and hyponatremia. The pathological process of CPM starts in the central pons near median raphe and spreads out “like a brush Fire” into the surrounding basis pontis. Extrapontine sites such as internal capsule, basal ganglia, cerebellum, and cerebrum can also be affected. We report a case of 60-year-old male with history of chronic alcoholism who presented to us with severe neurological deficits 10 days after his episode of severe hyponatremia. HOW TO CITE THIS ARTICLE: Tiwari R, Kumari A. Central Pontine Myelinolysis: A Case Report. Indian J Crit Care Med 2022;26(9):1049–1051.
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spelling pubmed-94927512022-10-07 Central Pontine Myelinolysis: A Case Report Tiwari, Richa Kumari, Anju Indian J Crit Care Med Case Report Central pontine myelinolysis (CPM) classically occurs due to rapid rise in serum osmolarity. Most cases have been associated with a history of chronic alcohol abuse, malnutrition, diuretic abuse, and hyponatremia. The pathological process of CPM starts in the central pons near median raphe and spreads out “like a brush Fire” into the surrounding basis pontis. Extrapontine sites such as internal capsule, basal ganglia, cerebellum, and cerebrum can also be affected. We report a case of 60-year-old male with history of chronic alcoholism who presented to us with severe neurological deficits 10 days after his episode of severe hyponatremia. HOW TO CITE THIS ARTICLE: Tiwari R, Kumari A. Central Pontine Myelinolysis: A Case Report. Indian J Crit Care Med 2022;26(9):1049–1051. Jaypee Brothers Medical Publishers 2022-09 /pmc/articles/PMC9492751/ /pubmed/36213701 http://dx.doi.org/10.5005/jp-journals-10071-24311 Text en Copyright © 2022; The Author(s). https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2022 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Tiwari, Richa
Kumari, Anju
Central Pontine Myelinolysis: A Case Report
title Central Pontine Myelinolysis: A Case Report
title_full Central Pontine Myelinolysis: A Case Report
title_fullStr Central Pontine Myelinolysis: A Case Report
title_full_unstemmed Central Pontine Myelinolysis: A Case Report
title_short Central Pontine Myelinolysis: A Case Report
title_sort central pontine myelinolysis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492751/
https://www.ncbi.nlm.nih.gov/pubmed/36213701
http://dx.doi.org/10.5005/jp-journals-10071-24311
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