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Central Pontine Myelinolysis: A Case Report
Central pontine myelinolysis (CPM) classically occurs due to rapid rise in serum osmolarity. Most cases have been associated with a history of chronic alcohol abuse, malnutrition, diuretic abuse, and hyponatremia. The pathological process of CPM starts in the central pons near median raphe and sprea...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Jaypee Brothers Medical Publishers
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492751/ https://www.ncbi.nlm.nih.gov/pubmed/36213701 http://dx.doi.org/10.5005/jp-journals-10071-24311 |
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author | Tiwari, Richa Kumari, Anju |
author_facet | Tiwari, Richa Kumari, Anju |
author_sort | Tiwari, Richa |
collection | PubMed |
description | Central pontine myelinolysis (CPM) classically occurs due to rapid rise in serum osmolarity. Most cases have been associated with a history of chronic alcohol abuse, malnutrition, diuretic abuse, and hyponatremia. The pathological process of CPM starts in the central pons near median raphe and spreads out “like a brush Fire” into the surrounding basis pontis. Extrapontine sites such as internal capsule, basal ganglia, cerebellum, and cerebrum can also be affected. We report a case of 60-year-old male with history of chronic alcoholism who presented to us with severe neurological deficits 10 days after his episode of severe hyponatremia. HOW TO CITE THIS ARTICLE: Tiwari R, Kumari A. Central Pontine Myelinolysis: A Case Report. Indian J Crit Care Med 2022;26(9):1049–1051. |
format | Online Article Text |
id | pubmed-9492751 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Jaypee Brothers Medical Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-94927512022-10-07 Central Pontine Myelinolysis: A Case Report Tiwari, Richa Kumari, Anju Indian J Crit Care Med Case Report Central pontine myelinolysis (CPM) classically occurs due to rapid rise in serum osmolarity. Most cases have been associated with a history of chronic alcohol abuse, malnutrition, diuretic abuse, and hyponatremia. The pathological process of CPM starts in the central pons near median raphe and spreads out “like a brush Fire” into the surrounding basis pontis. Extrapontine sites such as internal capsule, basal ganglia, cerebellum, and cerebrum can also be affected. We report a case of 60-year-old male with history of chronic alcoholism who presented to us with severe neurological deficits 10 days after his episode of severe hyponatremia. HOW TO CITE THIS ARTICLE: Tiwari R, Kumari A. Central Pontine Myelinolysis: A Case Report. Indian J Crit Care Med 2022;26(9):1049–1051. Jaypee Brothers Medical Publishers 2022-09 /pmc/articles/PMC9492751/ /pubmed/36213701 http://dx.doi.org/10.5005/jp-journals-10071-24311 Text en Copyright © 2022; The Author(s). https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2022 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Tiwari, Richa Kumari, Anju Central Pontine Myelinolysis: A Case Report |
title | Central Pontine Myelinolysis: A Case Report |
title_full | Central Pontine Myelinolysis: A Case Report |
title_fullStr | Central Pontine Myelinolysis: A Case Report |
title_full_unstemmed | Central Pontine Myelinolysis: A Case Report |
title_short | Central Pontine Myelinolysis: A Case Report |
title_sort | central pontine myelinolysis: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492751/ https://www.ncbi.nlm.nih.gov/pubmed/36213701 http://dx.doi.org/10.5005/jp-journals-10071-24311 |
work_keys_str_mv | AT tiwariricha centralpontinemyelinolysisacasereport AT kumarianju centralpontinemyelinolysisacasereport |