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Immune depletion of the methylated phenotype of colon cancer is closely related to resistance to immune checkpoint inhibitors

BACKGROUND: Molecular typing based on single omics data has its limitations and requires effective integration of multiple omics data for tumor typing of colorectal cancer (CRC). METHODS: Transcriptome expression, DNA methylation, somatic mutation, clinicopathological information, and copy number va...

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Detalles Bibliográficos
Autores principales: Zhong, Chengqian, Xie, Tingjiang, Chen, Long, Zhong, Xuejing, Li, Xinjing, Cai, Xiumei, Chen, Kaihong, Lan, Shiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492852/
https://www.ncbi.nlm.nih.gov/pubmed/36159794
http://dx.doi.org/10.3389/fimmu.2022.983636