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Immune depletion of the methylated phenotype of colon cancer is closely related to resistance to immune checkpoint inhibitors
BACKGROUND: Molecular typing based on single omics data has its limitations and requires effective integration of multiple omics data for tumor typing of colorectal cancer (CRC). METHODS: Transcriptome expression, DNA methylation, somatic mutation, clinicopathological information, and copy number va...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492852/ https://www.ncbi.nlm.nih.gov/pubmed/36159794 http://dx.doi.org/10.3389/fimmu.2022.983636 |