Cargando…

Immune depletion of the methylated phenotype of colon cancer is closely related to resistance to immune checkpoint inhibitors

BACKGROUND: Molecular typing based on single omics data has its limitations and requires effective integration of multiple omics data for tumor typing of colorectal cancer (CRC). METHODS: Transcriptome expression, DNA methylation, somatic mutation, clinicopathological information, and copy number va...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Chengqian, Xie, Tingjiang, Chen, Long, Zhong, Xuejing, Li, Xinjing, Cai, Xiumei, Chen, Kaihong, Lan, Shiqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492852/ https://www.ncbi.nlm.nih.gov/pubmed/36159794 http://dx.doi.org/10.3389/fimmu.2022.983636

Ejemplares similares

Granzyme B PET Imaging of Immune Checkpoint Inhibitor Combinations in Colon Cancer Phenotypes
por: Goggi, J. L., et al.
Publicado: (2020)

The effects of B cell depletion on immune related adverse events associated with immune checkpoint inhibition
por: Risbjerg, Rasmus Strøm, et al.
Publicado: (2020)

Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade
por: Jones, Keaton I, et al.
Publicado: (2018)

Immune Phenotype and Immune Checkpoint Inhibitors for the Treatment of Human Hepatocellular Carcinoma
por: Nishida, Naoshi, et al.
Publicado: (2020)

Biomarkers for immune checkpoint inhibition in sarcomas – are we close to clinical implementation?
por: Yiong, Chin Sern, et al.
Publicado: (2023)

Methionine deficiency facilitates antitumour immunity by altering m(6)A methylation of immune checkpoint transcripts
por: Li, Ting, et al.
Publicado: (2023)

Phenotypic Differences in Thyroid Immune Related Adverse Events Following Treatment With Immune Checkpoint Inhibitors
por: Muir, Christopher Alan, et al.
Publicado: (2021)

Rheumatic immune‐related adverse events induced by immune checkpoint inhibitors
por: Zhong, Hui, et al.
Publicado: (2020)

Spatiotemporal depletion of tumor-associated immune checkpoint PD-L1 with near-infrared photoimmunotherapy promotes antitumor immunity
por: Taki, Shunichi, et al.
Publicado: (2021)

Immune Checkpoints in Viral Infections
por: Cai, Huiming, et al.
Publicado: (2020)

Analysis of immune-related signatures of colorectal cancer identifying two different immune phenotypes: Evidence for immune checkpoint inhibitor therapy
por: Chen, Gang, et al.
Publicado: (2020)

Orchestration of immune checkpoints in tumor immune contexture and their prognostic significance in esophageal squamous cell carcinoma
por: Zhao, Jing-Jing, et al.
Publicado: (2018)

Depleting Tumor Cells Expressing Immune Checkpoint Ligands—A New Approach to Combat Cancer
por: Marcucci, Fabrizio, et al.
Publicado: (2021)

Cytokines and Immune Cell Phenotype in Acute Kidney Injury Associated With Immune Checkpoint Inhibitors
por: Farooqui, Naba, et al.
Publicado: (2022)

SYK Is Associated With Malignant Phenotype and Immune Checkpoints in Diffuse Glioma
por: Zhou, Quanwei, et al.
Publicado: (2022)

Colon Adenoma After Diagnosis of Immune Checkpoint Inhibitor-mediated Colitis
por: Machado, Antonio Pizuorno, et al.
Publicado: (2023)

Achievements and futures of immune checkpoint inhibitors in non-small cell lung cancer
por: Qiu, Zhenbin, et al.
Publicado: (2019)

Altered immune phenotype and DNA methylation in panic disorder
por: Petersen, Curtis L., et al.
Publicado: (2020)

Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune checkpoint inhibition
por: Saha, Achinto, et al.
Publicado: (2023)

The Proliferative Role of Immune Checkpoints in Tumors: Double Regulation
por: Tang, Xi-Yang, et al.
Publicado: (2022)

Hyperthermia combined with immune checkpoint inhibitor therapy in the treatment of primary and metastatic tumors
por: Yang, Ximing, et al.
Publicado: (2022)

Immune approaches beyond traditional immune checkpoint inhibitors for advanced renal cell carcinoma
por: Jang, Albert, et al.
Publicado: (2023)

Targeting immune checkpoints in malignant glioma
por: Zhang, Xuhao, et al.
Publicado: (2016)

Hypophysitis induced by immune checkpoint inhibitors in a Scottish melanoma population
por: Wei, Khor Zhong, et al.
Publicado: (2019)

Immune checkpoint inhibitors
por: Hui, Enfu
Publicado: (2019)

Immune checkpoint inhibitors
por: Kroemer, Guido, et al.
Publicado: (2021)

Immune checkpoint inhibitors in advanced cutaneous squamous cell carcinoma: A systemic review and meta‐analysis
por: Zhang, Haoran, et al.
Publicado: (2022)

Immune Checkpoint Inhibitors Related to Cardiotoxicity
por: Chen, Ru, et al.
Publicado: (2022)

Immune-related adverse events of immune checkpoint inhibitors: a review
por: Yin, Qinan, et al.
Publicado: (2023)

Clinical characteristics and outcomes of immune checkpoint inhibitor-induced diabetes mellitus
por: Liu, Jia, et al.
Publicado: (2022)

Neoadjuvant immune checkpoint inhibitor plus chemotherapy in rare tracheal tumors
por: Jiang, Ben‐Yuan, et al.
Publicado: (2021)

Immune checkpoint inhibitors in clinical trials
por: Sharon, Elad, et al.
Publicado: (2014)

Spatially targeted brain cancer immunotherapy with closed-loop controlled focused ultrasound and immune checkpoint blockade
por: Lee, Hohyun, et al.
Publicado: (2022)

DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma
por: Filipski, Katharina, et al.
Publicado: (2021)

Oncolytic vaccinia virus reinvigorates peritoneal immunity and cooperates with immune checkpoint inhibitor to suppress peritoneal carcinomatosis in colon cancer
por: Lee, Yu Seong, et al.
Publicado: (2020)

Comprehensive Analysis of the Immune Microenvironment in Checkpoint Inhibitor Pneumonitis
por: Lin, Xinqing, et al.
Publicado: (2022)

Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade
por: Bonavita, Eduardo, et al.
Publicado: (2020)

Immune checkpoint receptors: homeostatic regulators of immunity
por: Riva, Antonio, et al.
Publicado: (2018)

TET1 mutations as a predictive biomarker for immune checkpoint inhibitors in colon adenocarcinoma
por: Qiu, Tianzhu, et al.
Publicado: (2022)

Combinatorial therapeutic approaches of photodynamic therapy and immune checkpoint blockade for colon cancer treatment
por: Hao, Yang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nqe83ospj42iu3m66ba5vhnnde