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Effects of ilaprazole on the steady-state pharmacodynamics of clopidogrel in healthy volunteers: An open-label randomized crossover study

Background: Previous studies have suggested that proton pump inhibitors could impair the antiplatelet effect of clopidogrel. It is uncertain whether ilaprazole affects the antiplatelet effect of clopidogrel. This study aimed to determine the drug-drug interaction between ilaprazole and clopidogrel....

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Detalles Bibliográficos
Autores principales: Ye, Zekang, Chen, Pengsheng, Tan, Chuchu, Gong, Xiaoxuan, Li, Ran, Dong, Zhou, Ullah, Inam, Zhou, Chen, Zhou, Sufeng, Xie, Lijun, Hou, Xuemei, Han, Zhihui, Gu, Qian, Ma, Jiazheng, Teng, Jianzhen, Tang, Yingdan, Zhang, Zhuanxia, Hu, Haitang, Zhuang, Quankun, Chen, Juan, Zhu, Bei, Shao, Feng, Li, Chunjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492925/
https://www.ncbi.nlm.nih.gov/pubmed/36160382
http://dx.doi.org/10.3389/fphar.2022.952804