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Effects of ilaprazole on the steady-state pharmacodynamics of clopidogrel in healthy volunteers: An open-label randomized crossover study
Background: Previous studies have suggested that proton pump inhibitors could impair the antiplatelet effect of clopidogrel. It is uncertain whether ilaprazole affects the antiplatelet effect of clopidogrel. This study aimed to determine the drug-drug interaction between ilaprazole and clopidogrel....
Autores principales: | Ye, Zekang, Chen, Pengsheng, Tan, Chuchu, Gong, Xiaoxuan, Li, Ran, Dong, Zhou, Ullah, Inam, Zhou, Chen, Zhou, Sufeng, Xie, Lijun, Hou, Xuemei, Han, Zhihui, Gu, Qian, Ma, Jiazheng, Teng, Jianzhen, Tang, Yingdan, Zhang, Zhuanxia, Hu, Haitang, Zhuang, Quankun, Chen, Juan, Zhu, Bei, Shao, Feng, Li, Chunjian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492925/ https://www.ncbi.nlm.nih.gov/pubmed/36160382 http://dx.doi.org/10.3389/fphar.2022.952804 |
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