Cargando…
Using a competitive counterflow assay to identify novel cationic substrates of OATP1B1 and OATP1B3
OATP1B1 and OATP1B3 are two drug transporters that mediate the uptake of multiple endo- and xenobiotics, including many drugs, into human hepatocytes. Numerous inhibitors have been identified, and for some of them, it is not clear whether they are also substrates. Historically radiolabeled substrate...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493024/ https://www.ncbi.nlm.nih.gov/pubmed/36160869 http://dx.doi.org/10.3389/fphys.2022.969363 |