Virtual screening and activity evaluation of multitargeting inhibitors for idiopathic pulmonary fibrosis

Transforming growth factor β receptor (TGF-β1R) and receptor tyrosine kinases (RTKs), such as VEGFRs, PDGFRs and FGFRs are considered important therapeutic targets in blocking myofibroblast migration and activation of idiopathic pulmonary fibrosis (IPF). To screen and design innovative prodrug to si...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Xu, Jian, Yan, Rong, Liu, Huanbin, Zhao, Jingxin, Xie, Yuan, Deng, Wenbin, Liao, Weiping, Nie, Yichu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493029/
https://www.ncbi.nlm.nih.gov/pubmed/36160399
http://dx.doi.org/10.3389/fphar.2022.998245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493029/
https://www.ncbi.nlm.nih.gov/pubmed/36160399
http://dx.doi.org/10.3389/fphar.2022.998245

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