Cargando…

Calcium dobesilate efficiency in the treatment of diabetic kidney disease through suppressing MAPK and chemokine signaling pathways based on clinical evaluation and network pharmacology

Aims: To evaluate the effectiveness and potential mechanism of calcium dobesilate (CaD) in diabetic kidney disease (DKD) patients. Methods: We searched for available randomized controlled studies on DKD patients’ treatment with CaD through open databases. Continuous variables were expressed as stand...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Bingyu, Yin, Yanyan, Wang, Yuqing, Fu, Hui, Sun, Helin, Yue, Zhaodi, Yu, Shaohong, Zhang, Zhongwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493050/ https://www.ncbi.nlm.nih.gov/pubmed/36160448 http://dx.doi.org/10.3389/fphar.2022.850167

Ejemplares similares

Effect of dapagliflozin on diabetic patients with cardiovascular disease via MAPK signalling pathway
por: Yue, Zhaodi, et al.
Publicado: (2021)

Calcium Dobesilate Restores Autophagy by Inhibiting the VEGF/PI3K/AKT/mTOR Signaling Pathway
por: Wang, Yue, et al.
Publicado: (2019)

Combined treatment of diabetic nephropathy with alprostadil and calcium dobesilate
por: Qin, Lili, et al.
Publicado: (2017)

Mechanisms of retinal neuroprotection of calcium dobesilate: therapeutic implications
por: Simó-Servat, Olga, et al.
Publicado: (2017)

Calcium dobesilate-induced hyperpyrexia: A case report
por: Yang, Hui, et al.
Publicado: (2023)

Effect of Calcium Dobesilate in Preventing Contrast-Induced Nephropathy in Patients with Diabetes and Chronic Kidney Disease
por: Zhang, Hao, et al.
Publicado: (2021)

Bidirectional regulatory effects of Cordyceps on arrhythmia: Clinical evaluations and network pharmacology
por: Wang, Lijuan, et al.
Publicado: (2022)

Can calcium dobesilate be used safely for peripheral microvasculopathies that require neoangiogenesis?
por: Demirtas, Sinan, et al.
Publicado: (2013)

Calcium dobesilate may alleviate diabetes-induced endothelial dysfunction and inflammation
por: Zhou, Yijun, et al.
Publicado: (2017)

Selected Physicochemical Properties of Lyophilized Hydrogel with Liposomal Fraction of Calcium Dobesilate
por: Pilch, Ewa, et al.
Publicado: (2018)

Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice
por: Hakimizadeh, Elham, et al.
Publicado: (2022)

Modulation of the intramedullary pressure responses by calcium dobesilate in a rabbit knee model of osteoarthritis
por: Miles, James E, et al.
Publicado: (2011)

Therapeutic effects of calcium dobesilate on diabetic nephropathy mediated through reduction of expression of PAI-1
por: ZHANG, XIAOQIAN
Publicado: (2013)

Calcium Dobesilate Versus Flavonoids for the Treatment of Early Hemorrhoidal Disease: A Randomized Controlled Trial
por: Changazi, Shabbar H, et al.
Publicado: (2020)

A new method for anti‐negative interference of calcium dobesilate in serum creatinine enzymatic analysis
por: Shen, Hailan, et al.
Publicado: (2021)

Simultaneous estimation of troxerutin and calcium dobesilate in presence of the carcinogenic hydroquinone using green spectrofluorimetric method
por: Tolba, M. M., et al.
Publicado: (2021)

Chemokine Receptor 5, a Double-Edged Sword in Metabolic Syndrome and Cardiovascular Disease
por: Zhang, Zhongwen, et al.
Publicado: (2020)

Pharmacological mechanisms of Fuzheng Huayu formula for Aristolochic acid I–induced kidney fibrosis through network pharmacology
por: Wang, Fan, et al.
Publicado: (2022)

Rhein for treating diabetes mellitus: A pharmacological and mechanistic overview
por: Deng, Tingting, et al.
Publicado: (2023)

QishenYiqi dripping pill protects against myocardial ischemia/reperfusion injury via suppressing excessive autophagy and NLRP3 inflammasome based on network pharmacology and experimental pharmacology
por: Li, Meng, et al.
Publicado: (2022)

Strong Negative Interference by Calcium Dobesilate in Sarcosine Oxidase Assays for Serum Creatinine Involving the Trinder Reaction
por: Guo, Xiuzhi, et al.
Publicado: (2015)

Negative interferences by calcium dobesilate in the detection of five serum analytes involving Trinder reaction-based assays
por: Guo, Xiuzhi, et al.
Publicado: (2018)

Investigation of the Mechanism Underlying Calcium Dobesilate-Mediated Improvement of Endothelial Dysfunction and Inflammation Caused by High Glucose
por: Zhou, Yijun, et al.
Publicado: (2019)

Calcium Dobesilate (CaD) Attenuates High Glucose and High Lipid-Induced Impairment of Sarcoplasmic Reticulum Calcium Handling in Cardiomyocytes
por: Deng, Jianxin, et al.
Publicado: (2021)

Calcium Dobesilate Inhibits the Alterations in Tight Junction Proteins and Leukocyte Adhesion to Retinal Endothelial Cells Induced by Diabetes
por: Leal, Ermelindo C., et al.
Publicado: (2010)

The modulation of gut microbiota by herbal medicine to alleviate diabetic kidney disease – A review
por: Du, Jinxin, et al.
Publicado: (2022)

Network Pharmacology and Pharmacological Evaluation Reveals the Mechanism of the Sanguisorba Officinalis in Suppressing Hepatocellular Carcinoma
por: Jiang, Nan, et al.
Publicado: (2021)

Short-term efficacy of intravitreal dobesilate in central serous chorioretinopathy
por: Cuevas, Pedro, et al.
Publicado: (2012)

Dramatic resolution of vitreous hemorrhage after an intravitreal injection of dobesilate
por: Cuevas, Pedro, et al.
Publicado: (2015)

Effect of Chinese Patent Medicines on Ocular Fundus Signs and Vision in Calcium Dobesilate-Treated Persons With Non-Proliferative Diabetic Retinopathy: A Systematic Review and Meta-Analysis
por: Zhang, Yuehong, et al.
Publicado: (2022)

Calcium dobesilate reduces endothelin-1 and high-sensitivity C-reactive protein serum levels in patients with diabetic retinopathy
por: Javadzadeh, Alireza, et al.
Publicado: (2013)

Effects of calcium dobesilate on Nrf2, Keap1 and HO-1 in the lenses of D-galactose-induced cataracts in rats
por: Sun, Jinfeng, et al.
Publicado: (2018)

Calcium dobesilate reduces SARS-CoV-2 entry into endothelial cells by inhibiting virus binding to heparan sulfate
por: Kiyan, Yulia, et al.
Publicado: (2022)

Calcium dobesilate alleviates renal dysfunction and inflammation by targeting nuclear factor kappa B (NF-κB) signaling in sepsis-associated acute kidney injury
por: Xie, Zhijuan, et al.
Publicado: (2022)

Chemokines in Alzheimer’s Disease: New Insights Into Prokineticins, Chemokine-Like Proteins
por: Zuena, Anna Rita, et al.
Publicado: (2019)

Maslinic Acid Attenuates Ischemia/Reperfusion-Induced Acute Kidney Injury by Suppressing Inflammation and Apoptosis Through Inhibiting NF-κB and MAPK Signaling Pathway
por: Sun, Wenjuan, et al.
Publicado: (2022)

Chuanxiong improves angiogenesis via the PI3K/AKT/Ras/MAPK pathway based on network pharmacology and DESI-MSI metabolomics
por: Cheng, Xue-hao, et al.
Publicado: (2023)

Suppression of Medulloblastoma Lesions by Forced Migration of Preneoplastic Precursor Cells with Intracerebellar Administration of the Chemokine Cxcl3
por: Ceccarelli, Manuela, et al.
Publicado: (2016)

Aprepitant Inhibits JNK and p38/MAPK to Attenuate Inflammation and Suppresses Inflammatory Pain
por: Yang, Yang, et al.
Publicado: (2022)

Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs
por: Korinek, Michal, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_npker39ld1t4v573mu0o7km0kn