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Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults

Sleep deprivation is associated with dysregulation of the autonomic nervous system, adverse cardiovascular events, cognitive and complex motor performance impairment. Less is known about the effects of acute total sleep deprivation (ATSD) on physiological coupling. We aimed to determine the effects...

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Autores principales: Liu, Hongyun, Yu, Xiaohua, Wang, Guojing, Han, Yi, Wang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493191/
https://www.ncbi.nlm.nih.gov/pubmed/36161147
http://dx.doi.org/10.3389/fnins.2022.952329
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author Liu, Hongyun
Yu, Xiaohua
Wang, Guojing
Han, Yi
Wang, Weidong
author_facet Liu, Hongyun
Yu, Xiaohua
Wang, Guojing
Han, Yi
Wang, Weidong
author_sort Liu, Hongyun
collection PubMed
description Sleep deprivation is associated with dysregulation of the autonomic nervous system, adverse cardiovascular events, cognitive and complex motor performance impairment. Less is known about the effects of acute total sleep deprivation (ATSD) on physiological coupling. We aimed to determine the effects of 24-h ATSD on the physiological coupling between complex subsystems by evaluating the cardiorespiratory, cardiovascular and cortico-cardiac interactions. This study enrolled 38 young healthy participants aged 23.2 ± 2.4 years. Multiple synchronous physiological signals including electrocardiography, photoplethysmography, bio-electrical impedance, electroencephalography, and continuous hemodynamic data, were performed over a baseline night after regular sleep and after a night with 24-h ATSD in the supine position. The magnitude squared coherence, phase synchronization index, and heartbeat evoked potential amplitudes, were obtained from 10-min synchronous physiological recordings to estimate the coupling strength between two time series. Parameters of hemodynamic characteristics and heart rate variability were also calculated to quantify autonomic regulation. Results indicated that the magnitude squared coherence (0.38 ± 0.17 vs. 0.29 ± 0.12, p = 0.015) between respiration and heart rate variability along with the magnitude squared coherence (0.36 ± 0.18 vs. 0.27 ± 0.13, p = 0.012) between respiration and pulse transit time were significantly decreased after 24-h ATSD. There were no significant differences (all p > 0.05) in phase synchronization indices, heartbeat evoked potential amplitudes as well as other analyzed measurements between baseline and 24-h ATSD states. We conclude that exposure to 24-h ATSD appears to weaken the cardiorespiratory and respiratory-cardiovascular coupling strength of young healthy adults. These findings suggest that physiological coupling analysis may serve as a complementary approach for characterizing and understanding the complex effects of sleep deprivation.
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spelling pubmed-94931912022-09-23 Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults Liu, Hongyun Yu, Xiaohua Wang, Guojing Han, Yi Wang, Weidong Front Neurosci Neuroscience Sleep deprivation is associated with dysregulation of the autonomic nervous system, adverse cardiovascular events, cognitive and complex motor performance impairment. Less is known about the effects of acute total sleep deprivation (ATSD) on physiological coupling. We aimed to determine the effects of 24-h ATSD on the physiological coupling between complex subsystems by evaluating the cardiorespiratory, cardiovascular and cortico-cardiac interactions. This study enrolled 38 young healthy participants aged 23.2 ± 2.4 years. Multiple synchronous physiological signals including electrocardiography, photoplethysmography, bio-electrical impedance, electroencephalography, and continuous hemodynamic data, were performed over a baseline night after regular sleep and after a night with 24-h ATSD in the supine position. The magnitude squared coherence, phase synchronization index, and heartbeat evoked potential amplitudes, were obtained from 10-min synchronous physiological recordings to estimate the coupling strength between two time series. Parameters of hemodynamic characteristics and heart rate variability were also calculated to quantify autonomic regulation. Results indicated that the magnitude squared coherence (0.38 ± 0.17 vs. 0.29 ± 0.12, p = 0.015) between respiration and heart rate variability along with the magnitude squared coherence (0.36 ± 0.18 vs. 0.27 ± 0.13, p = 0.012) between respiration and pulse transit time were significantly decreased after 24-h ATSD. There were no significant differences (all p > 0.05) in phase synchronization indices, heartbeat evoked potential amplitudes as well as other analyzed measurements between baseline and 24-h ATSD states. We conclude that exposure to 24-h ATSD appears to weaken the cardiorespiratory and respiratory-cardiovascular coupling strength of young healthy adults. These findings suggest that physiological coupling analysis may serve as a complementary approach for characterizing and understanding the complex effects of sleep deprivation. Frontiers Media S.A. 2022-09-08 /pmc/articles/PMC9493191/ /pubmed/36161147 http://dx.doi.org/10.3389/fnins.2022.952329 Text en Copyright © 2022 Liu, Yu, Wang, Han and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Liu, Hongyun
Yu, Xiaohua
Wang, Guojing
Han, Yi
Wang, Weidong
Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults
title Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults
title_full Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults
title_fullStr Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults
title_full_unstemmed Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults
title_short Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults
title_sort effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493191/
https://www.ncbi.nlm.nih.gov/pubmed/36161147
http://dx.doi.org/10.3389/fnins.2022.952329
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