Cargando…

The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review

To assess the impact of topical agents and dressings on surface wound pH, temperature, and subsequent wound healing. This was a systematic, narrative review of the literature, following the PRISMA (2020) guidelines. The databases searched were Medline PubMed, Cumulative Index to Nursing and Allied H...

Descripción completa

Detalles Bibliográficos
Autores principales: Derwin, Rosemarie, Patton, Declan, Avsar, Pinar, Strapp, Helen, Moore, Zena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493238/
https://www.ncbi.nlm.nih.gov/pubmed/34931445
http://dx.doi.org/10.1111/iwj.13733
_version_ 1784793659468677120
author Derwin, Rosemarie
Patton, Declan
Avsar, Pinar
Strapp, Helen
Moore, Zena
author_facet Derwin, Rosemarie
Patton, Declan
Avsar, Pinar
Strapp, Helen
Moore, Zena
author_sort Derwin, Rosemarie
collection PubMed
description To assess the impact of topical agents and dressings on surface wound pH, temperature, and subsequent wound healing. This was a systematic, narrative review of the literature, following the PRISMA (2020) guidelines. The databases searched were Medline PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Cochrane Library, Embase, Web of Science, and Scopus. Data synthesis and analysis were conducted using a structured narrative synthesis. The quality of the included clinical studies was appraised using the Evidence‐Based Literature (EBL) Critical Appraisal Tool. A total of six clinical studies were assessed as eligible for inclusion, A total of six dressings/topical agents were assessed and the types of wounds included non‐healing chronic wounds. Of the studies, five explored pH and one explored temperature. The EBL validity of the clinical studies was low (mean quality score was 51.3%). The five clinical studies that explored pH investigated different dressings and topical agents reporting an associated reduction in pH and improved wound outcomes. One clinical study investigated the impact of topical sodium nitrite on temperature and found that sodium nitrite increased peri‐wound skin temperature and improved wound outcomes with a reduction in leg ulcer size. Given the low certainty of the evidence, we cannot confidently recommend the use of any particular topical agent or dressing to manipulate pH, or temperature to improve wound outcomes. Thus, there is a need for further research to develop a greater understanding of this topic. Irish Research Council, Enterprise Partnership Scheme.
format Online
Article
Text
id pubmed-9493238
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Blackwell Publishing Ltd
record_format MEDLINE/PubMed
spelling pubmed-94932382022-09-30 The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review Derwin, Rosemarie Patton, Declan Avsar, Pinar Strapp, Helen Moore, Zena Int Wound J Original Articles To assess the impact of topical agents and dressings on surface wound pH, temperature, and subsequent wound healing. This was a systematic, narrative review of the literature, following the PRISMA (2020) guidelines. The databases searched were Medline PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Cochrane Library, Embase, Web of Science, and Scopus. Data synthesis and analysis were conducted using a structured narrative synthesis. The quality of the included clinical studies was appraised using the Evidence‐Based Literature (EBL) Critical Appraisal Tool. A total of six clinical studies were assessed as eligible for inclusion, A total of six dressings/topical agents were assessed and the types of wounds included non‐healing chronic wounds. Of the studies, five explored pH and one explored temperature. The EBL validity of the clinical studies was low (mean quality score was 51.3%). The five clinical studies that explored pH investigated different dressings and topical agents reporting an associated reduction in pH and improved wound outcomes. One clinical study investigated the impact of topical sodium nitrite on temperature and found that sodium nitrite increased peri‐wound skin temperature and improved wound outcomes with a reduction in leg ulcer size. Given the low certainty of the evidence, we cannot confidently recommend the use of any particular topical agent or dressing to manipulate pH, or temperature to improve wound outcomes. Thus, there is a need for further research to develop a greater understanding of this topic. Irish Research Council, Enterprise Partnership Scheme. Blackwell Publishing Ltd 2021-12-20 /pmc/articles/PMC9493238/ /pubmed/34931445 http://dx.doi.org/10.1111/iwj.13733 Text en © 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Derwin, Rosemarie
Patton, Declan
Avsar, Pinar
Strapp, Helen
Moore, Zena
The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review
title The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review
title_full The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review
title_fullStr The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review
title_full_unstemmed The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review
title_short The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review
title_sort impact of topical agents and dressing on ph and temperature on wound healing: a systematic, narrative review
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493238/
https://www.ncbi.nlm.nih.gov/pubmed/34931445
http://dx.doi.org/10.1111/iwj.13733
work_keys_str_mv AT derwinrosemarie theimpactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview
AT pattondeclan theimpactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview
AT avsarpinar theimpactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview
AT strapphelen theimpactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview
AT moorezena theimpactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview
AT derwinrosemarie impactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview
AT pattondeclan impactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview
AT avsarpinar impactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview
AT strapphelen impactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview
AT moorezena impactoftopicalagentsanddressingonphandtemperatureonwoundhealingasystematicnarrativereview