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The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review
To assess the impact of topical agents and dressings on surface wound pH, temperature, and subsequent wound healing. This was a systematic, narrative review of the literature, following the PRISMA (2020) guidelines. The databases searched were Medline PubMed, Cumulative Index to Nursing and Allied H...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493238/ https://www.ncbi.nlm.nih.gov/pubmed/34931445 http://dx.doi.org/10.1111/iwj.13733 |
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author | Derwin, Rosemarie Patton, Declan Avsar, Pinar Strapp, Helen Moore, Zena |
author_facet | Derwin, Rosemarie Patton, Declan Avsar, Pinar Strapp, Helen Moore, Zena |
author_sort | Derwin, Rosemarie |
collection | PubMed |
description | To assess the impact of topical agents and dressings on surface wound pH, temperature, and subsequent wound healing. This was a systematic, narrative review of the literature, following the PRISMA (2020) guidelines. The databases searched were Medline PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Cochrane Library, Embase, Web of Science, and Scopus. Data synthesis and analysis were conducted using a structured narrative synthesis. The quality of the included clinical studies was appraised using the Evidence‐Based Literature (EBL) Critical Appraisal Tool. A total of six clinical studies were assessed as eligible for inclusion, A total of six dressings/topical agents were assessed and the types of wounds included non‐healing chronic wounds. Of the studies, five explored pH and one explored temperature. The EBL validity of the clinical studies was low (mean quality score was 51.3%). The five clinical studies that explored pH investigated different dressings and topical agents reporting an associated reduction in pH and improved wound outcomes. One clinical study investigated the impact of topical sodium nitrite on temperature and found that sodium nitrite increased peri‐wound skin temperature and improved wound outcomes with a reduction in leg ulcer size. Given the low certainty of the evidence, we cannot confidently recommend the use of any particular topical agent or dressing to manipulate pH, or temperature to improve wound outcomes. Thus, there is a need for further research to develop a greater understanding of this topic. Irish Research Council, Enterprise Partnership Scheme. |
format | Online Article Text |
id | pubmed-9493238 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Blackwell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-94932382022-09-30 The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review Derwin, Rosemarie Patton, Declan Avsar, Pinar Strapp, Helen Moore, Zena Int Wound J Original Articles To assess the impact of topical agents and dressings on surface wound pH, temperature, and subsequent wound healing. This was a systematic, narrative review of the literature, following the PRISMA (2020) guidelines. The databases searched were Medline PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Cochrane Library, Embase, Web of Science, and Scopus. Data synthesis and analysis were conducted using a structured narrative synthesis. The quality of the included clinical studies was appraised using the Evidence‐Based Literature (EBL) Critical Appraisal Tool. A total of six clinical studies were assessed as eligible for inclusion, A total of six dressings/topical agents were assessed and the types of wounds included non‐healing chronic wounds. Of the studies, five explored pH and one explored temperature. The EBL validity of the clinical studies was low (mean quality score was 51.3%). The five clinical studies that explored pH investigated different dressings and topical agents reporting an associated reduction in pH and improved wound outcomes. One clinical study investigated the impact of topical sodium nitrite on temperature and found that sodium nitrite increased peri‐wound skin temperature and improved wound outcomes with a reduction in leg ulcer size. Given the low certainty of the evidence, we cannot confidently recommend the use of any particular topical agent or dressing to manipulate pH, or temperature to improve wound outcomes. Thus, there is a need for further research to develop a greater understanding of this topic. Irish Research Council, Enterprise Partnership Scheme. Blackwell Publishing Ltd 2021-12-20 /pmc/articles/PMC9493238/ /pubmed/34931445 http://dx.doi.org/10.1111/iwj.13733 Text en © 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Derwin, Rosemarie Patton, Declan Avsar, Pinar Strapp, Helen Moore, Zena The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review |
title | The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review |
title_full | The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review |
title_fullStr | The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review |
title_full_unstemmed | The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review |
title_short | The impact of topical agents and dressing on pH and temperature on wound healing: A systematic, narrative review |
title_sort | impact of topical agents and dressing on ph and temperature on wound healing: a systematic, narrative review |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493238/ https://www.ncbi.nlm.nih.gov/pubmed/34931445 http://dx.doi.org/10.1111/iwj.13733 |
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