Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression

Hepatocytes secrete retinol-binding protein 4 (RBP4) into circulation, thereby mobilizing vitamin A from the liver to provide retinol for extrahepatic tissues. Obesity and insulin resistance are associated with elevated RBP4 levels in the blood. However, in a previous study, we observed that chronic...

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Detalles Bibliográficos
Autores principales: Steinhoff, Julia S., Wagner, Carina, Taschler, Ulrike, Wulff, Sascha, Kiefer, Marie F., Petricek, Konstantin M., Wowro, Sylvia J., Oster, Moritz, Flores, Roberto E., Yang, Na, Li, Chen, Meng, Yueming, Sommerfeld, Manuela, Weger, Stefan, Henze, Andrea, Raila, Jens, Lass, Achim, Schupp, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493389/
https://www.ncbi.nlm.nih.gov/pubmed/36030930
http://dx.doi.org/10.1016/j.jlr.2022.100268

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