An ELISA-based platform for rapid identification of structure-dependent nucleic acid–protein interactions detects novel DNA triplex interactors

Unusual nucleic acid structures play vital roles as intermediates in many cellular processes and, in the case of peptide nucleic acid (PNA)–mediated triplexes, are leveraged as tools for therapeutic gene editing. However, due to their transient nature, an understanding of the factors that interact w...

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Detalles Bibliográficos
Autores principales: Economos, Nicholas G., Thapar, Upasna, Balasubramanian, Nanda, Karras, Georgios I., Glazer, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493393/
https://www.ncbi.nlm.nih.gov/pubmed/35988651
http://dx.doi.org/10.1016/j.jbc.2022.102398

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