Cargando…

Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

BACKGROUND: Serum neurofilament light (sNfL) chain is a promising biomarker reflecting neuro-axonal injury in multiple sclerosis (MS). However, the ability of sNfL to predict outcomes in real-world MS cohorts requires further validation. OBJECTIVE: The aim of the study is to investigate the associat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brune, Synne, Høgestøl, Einar A, de Rodez Benavent, Sigrid A, Berg-Hansen, Pål, Beyer, Mona K, Leikfoss, Ingvild Sørum, Bos, Steffan D, Sowa, Piotr, Brunborg, Cathrine, Andorra, Magi, Pulido Valdeolivas, Irene, Asseyer, Susanna, Brandt, Alexander, Chien, Claudia, Scheel, Michael, Blennow, Kaj, Zetterberg, Henrik, Kerlero de Rosbo, Nicole, Paul, Friedemann, Uccelli, Antonio, Villoslada, Pablo, Berge, Tone, Harbo, Hanne F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Original Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493412/ https://www.ncbi.nlm.nih.gov/pubmed/35658739 http://dx.doi.org/10.1177/13524585221097296

Ejemplares similares

Brain disconnectome mapping derived from white matter lesions and serum neurofilament light levels in multiple sclerosis: A longitudinal multicenter study
por: Rise, Henning H., et al.
Publicado: (2022)

From Identification to Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A
por: Berge, Tone, et al.
Publicado: (2013)

Impact of treatment on cellular immunophenotype in MS: A cross-sectional study
por: Cellerino, Maria, et al.
Publicado: (2020)

Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls
por: Cappelletti, Chiara, et al.
Publicado: (2022)

LesionQuant for Assessment of MRI in Multiple Sclerosis—A Promising Supplement to the Visual Scan Inspection
por: Brune, Synne, et al.
Publicado: (2020)

No differential gene expression for CD4(+) T cells of MS patients and healthy controls
por: Brorson, Ina S, et al.
Publicado: (2019)

Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19
por: Aamodt, Anne Hege, et al.
Publicado: (2021)

Bone Marrow Transfer in Relapsing-Remitting EAE Ameliorates Disease at First Remission, with No Synergistic Effect upon Co-Transplantation with Mesenchymal Stem Cells
por: Ferrara, Giovanni, et al.
Publicado: (2021)

Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response
por: Parodi, Benedetta, et al.
Publicado: (2021)

Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells
por: Leikfoss, Ingvild S., et al.
Publicado: (2015)

Genome-Wide DNA Methylation Profiles Indicate CD8+ T Cell Hypermethylation in Multiple Sclerosis
por: Bos, Steffan D., et al.
Publicado: (2015)

The Gut-Brain Axis in Multiple Sclerosis. Is Its Dysfunction a Pathological Trigger or a Consequence of the Disease?
por: Parodi, Benedetta, et al.
Publicado: (2021)

Regulatory Functions of Natural Killer Cells in Multiple Sclerosis
por: Gross, Catharina C., et al.
Publicado: (2016)

Teriflunomide treatment reduces B cells in patients with MS
por: Gandoglia, Ilaria, et al.
Publicado: (2017)

Ocrelizumab does not impair B- and T-cell responses to primary VZV infection in a patient with MS
por: Novi, Giovanni, et al.
Publicado: (2020)

Role of miRNAs shuttled by mesenchymal stem cell-derived small extracellular vesicles in modulating neuroinflammation
por: Giunti, Debora, et al.
Publicado: (2021)

Exploring Retinal Blood Vessel Diameters as Biomarkers in Multiple Sclerosis
por: Drobnjak Nes, Dragana, et al.
Publicado: (2022)

A Longitudinal Study of Disability, Cognition and Gray Matter Atrophy in Early Multiple Sclerosis Patients According to Evidence of Disease Activity
por: Nygaard, Gro O., et al.
Publicado: (2015)

Different Susceptibility of T and B Cells to Cladribine Depends On Their Levels of Deoxycytidine Kinase Activity Linked to Activation Status
por: Carlini, Federico, et al.
Publicado: (2021)

Neurodegenerative Interplay of Cardiovascular Autonomic Dysregulation and the Retina in Early Multiple Sclerosis
por: de Rodez Benavent, Sigrid A., et al.
Publicado: (2019)

Cortical fractal dimension predicts disability worsening in Multiple Sclerosis patients
por: Roura, Eloy, et al.
Publicado: (2021)

Quantitative proteomic analyses of CD4(+) and CD8(+) T cells reveal differentially expressed proteins in multiple sclerosis patients and healthy controls
por: Berge, Tone, et al.
Publicado: (2019)

Epigenome-wide association study of peripheral immune cell populations in Parkinson’s disease
por: Andersen, Maren Stolp, et al.
Publicado: (2023)

Defining the role of NG2-expressing cells in experimental models of multiple sclerosis. A biofunctional analysis of the neurovascular unit in wild type and NG2 null mice
por: Girolamo, Francesco, et al.
Publicado: (2019)

Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF
por: Buffolo, Federica, et al.
Publicado: (2021)

Microglia-derived CCL2 has a prime role in neocortex neuroinflammation
por: Errede, Mariella, et al.
Publicado: (2022)

Correction: Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF
por: Buffolo, Federica, et al.
Publicado: (2023)

Fatigue and cognition: Pupillary responses to problem‐solving in early multiple sclerosis patients
por: de Rodez Benavent, Sigrid A., et al.
Publicado: (2017)

Dynamics and heterogeneity of brain damage in multiple sclerosis
por: Kotelnikova, Ekaterina, et al.
Publicado: (2017)

NG2, a common denominator for neuroinflammation, blood–brain barrier alteration, and oligodendrocyte precursor response in EAE, plays a role in dendritic cell activation
por: Ferrara, Giovanni, et al.
Publicado: (2016)

Predictors of vision impairment in Multiple Sclerosis
por: Sanchez-Dalmau, Bernardo, et al.
Publicado: (2018)

Irritable bowel syndrome-like symptoms and health related quality of life two years after Roux-en-Y gastric bypass - a prospective cohort study
por: Blom-Høgestøl, Ingvild Kristine, et al.
Publicado: (2019)

In Vivo Molecular Changes in the Retina of Patients With Multiple Sclerosis
por: Alba-Arbalat, Salut, et al.
Publicado: (2021)

Micro-RNAs Shuttled by Extracellular Vesicles Secreted from Mesenchymal Stem Cells Dampen Astrocyte Pathological Activation and Support Neuroprotection in In-Vitro Models of ALS
por: Provenzano, Francesca, et al.
Publicado: (2022)

Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS
por: Parodi, Benedetta, et al.
Publicado: (2015)

Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer’s mice
por: Santamaria, Giulia, et al.
Publicado: (2020)

Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease
por: Mattsson, Niklas, et al.
Publicado: (2017)

Neurofilament light and tau as blood biomarkers for sports-related concussion
por: Shahim, Pashtun, et al.
Publicado: (2018)

‘Multi-Epitope-Targeted’ Immune-Specific Therapy for a Multiple Sclerosis-Like Disease via Engineered Multi-Epitope Protein Is Superior to Peptides
por: Kaushansky, Nathali, et al.
Publicado: (2011)

Tau or neurofilament light—Which is the more suitable biomarker for Huntington’s disease?
por: Niemelä, Valter, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1561q2vcbm2amk2cl967qi3jpc