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Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis

BACKGROUND: Cytochrome P450 Family 1 Subfamily A Member 1 (CYP1A1) pathway, which is regulated by aryl hydrocarbon receptor (AhR) plays an important role in chemical carcinogenesis and xenobiotic metabolism. Recently, we demonstrated that the microbial metabolite Urolithin A (UroA) mitigates colitis...

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Detalles Bibliográficos
Autores principales:	Ghosh, Sweta, Moorthy, Bhagavatula, Haribabu, Bodduluri, Jala, Venkatakrishna Rao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493474/ https://www.ncbi.nlm.nih.gov/pubmed/36159798 http://dx.doi.org/10.3389/fimmu.2022.1004603

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