Cargando…
Tuning a high performing multiplexed-CRISPRi Pseudomonas putida strain to further enhance indigoidine production
In this study, a 14-gene edited Pseudomonas putida KT2440 strain for heterologous indigoidine production was examined using three distinct omic datasets. Transcriptomic data indicated that CRISPR/dCpf1-interference (CRISPRi) mediated multiplex repression caused global gene expression changes, implyi...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494242/ https://www.ncbi.nlm.nih.gov/pubmed/36158112 http://dx.doi.org/10.1016/j.mec.2022.e00206 |