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Tuning a high performing multiplexed-CRISPRi Pseudomonas putida strain to further enhance indigoidine production

In this study, a 14-gene edited Pseudomonas putida KT2440 strain for heterologous indigoidine production was examined using three distinct omic datasets. Transcriptomic data indicated that CRISPR/dCpf1-interference (CRISPRi) mediated multiplex repression caused global gene expression changes, implyi...

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Detalles Bibliográficos
Autores principales:	Czajka, Jeffrey J., Banerjee, Deepanwita, Eng, Thomas, Menasalvas, Javier, Yan, Chunsheng, Munoz, Nathalie Munoz, Poirier, Brenton C., Kim, Young-Mo, Baker, Scott E., Tang, Yinjie J., Mukhopadhyay, Aindrila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494242/ https://www.ncbi.nlm.nih.gov/pubmed/36158112 http://dx.doi.org/10.1016/j.mec.2022.e00206

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